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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016 William H. Rosenblatt
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THE PHARMACOLOGY OF NEW SHORT-ACTING NONDEPOLARIZING ESTER NEUROMUSCULAR BLOCKING AGENTS
Survey of Anesthesiology, 1974 J. J. SAVARESE +3 more
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Resistance to Nondepolarizing Neuromuscular Blocking Agents
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1996Several case reports of resistance to short‐term administration of nondepolarizing neuromuscular blocking agents (NNMBAs) have been reported in research and surgical settings. Recently, several reports documented resistance to NNMBAs during therapy for prolonged paralysis in critically ill patients. Adverse outcomes associated with NNMBA resistance may
S J, Tschida +3 more
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[Neuromuscular blockade. Dosage of nondepolarizing agents to risk-group patients].
Ugeskrift for laeger, 1995 Holst Pe, Doris Østergaard, Jan Bonde
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An analytical pharmacodynamic model for nondepolarizing neuromuscular blocking agents
Journal of Pharmacokinetics and Biopharmaceutics, 1981A pharmacodynamic model for nondepolarizing neuromuscular blocking agents (NMBA) is developed and tested with different sets of data (NMBA plasma concentration and time evolution of muscular paralysis). This model takes into account the binding of NMBA to the cholinergic motor endplate receptors and thus permits estimation of the apparent equilibrium ...
D'Hollander, Alain, Delcroix, Claude
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Anesthesia & Analgesia, 2017
BACKGROUND:Nondepolarizing neuromuscular blocking drugs (NNMBDs) are commonly used as an adjunct to general anesthesia. Residual blockade is common, but its potential adverse effects are incompletely known. This study was designed to assess the association between NNMBD use with or without neostigmine reversal and postoperative morbidity and mortality ...
Michael R, Bronsert +8 more
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BACKGROUND:Nondepolarizing neuromuscular blocking drugs (NNMBDs) are commonly used as an adjunct to general anesthesia. Residual blockade is common, but its potential adverse effects are incompletely known. This study was designed to assess the association between NNMBD use with or without neostigmine reversal and postoperative morbidity and mortality ...
Michael R, Bronsert +8 more
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The role of nondepolarizing neuromuscular blocking agents in mechanically ventilated patients.
Journal of the Medical Association of Georgia, 1995Prolonged use of the nondepolarizing neuromuscular blocking agents in the critical care setting has greatly increased in the recent past. Accompanying the increased use of these agents are numerous accounts of long-lasting adverse outcomes such as muscular atrophy and neuropathy that can be attributed to pharmacologic paralysis.
J R, May, A F, Rutkowski
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Canadian journal of anesthesia-Journal canadien d anesthesie, 1994
Three muscle relaxants, Org 9453, Org 9489 and Org 9487, short-acting in animals, were investigated to establish their profiles in humans. Potency, time course of action, and pharmacokinetic behaviour were studied in 90 healthy patients during fentanyl/halothane/N2O anaesthesia. Neuromuscular function was monitored mechanomyographically.
WIERDA, JMKH +4 more
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Three muscle relaxants, Org 9453, Org 9489 and Org 9487, short-acting in animals, were investigated to establish their profiles in humans. Potency, time course of action, and pharmacokinetic behaviour were studied in 90 healthy patients during fentanyl/halothane/N2O anaesthesia. Neuromuscular function was monitored mechanomyographically.
WIERDA, JMKH +4 more
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Steven P Rowe, Martin G Pomper
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