Results 91 to 100 of about 33,933 (226)

Neuron-specific enolase, histopathological types, and age as risk factors for bone metastases in lung cancer

open access: yesTumor Biology, 2017
Lung cancer is a malignant tumor with high metastatic ability and bone is the most common site of distant metastasis of it. However, the independent risk factors for bone metastases of lung cancer remain largely to be elucidated.
Yang Zhou   +5 more
doaj   +1 more source

Key inflammatory pathway activations in the MCI stage of Alzheimer's disease [PDF]

open access: yes, 2019
OBJECTIVE: To determine the key inflammatory pathways that are activated in the peripheral and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease (AD).
Bekris, Lynn M.   +7 more
core   +2 more sources

Fractionated Gamma Knife Radiation for Papillary Tumor of the Pineal Region: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Papillary tumor of the pineal region (PTPR) is a rare central nervous system neoplasm with an unpredictable clinical course. Gross total resection, the preferred treatment, is often unachievable due to the tumor's deep‐seated location, necessitating alternative therapies.
Arad Iranmehr   +6 more
wiley   +1 more source

BACH2 alleviates immune checkpoint inhibitors‐induced cardiac pyroptosis via transcriptionally promoting GRSF1

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Immune checkpoint inhibitors cause elevated cardiac injuries in humans and mice. ICIs cause myocyte pyroptosis and cardiotoxicity, not via the adaptive immune system BACH2 ameliorates ICIs‐induced pyroptosis through transcriptionally promoting GRSF1. Lipoic acid, as a transcriptional inducer of BACH2, suppresses ICIs‐induced cardiotoxicity.
Mengying Cao   +9 more
wiley   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann   +6 more
wiley   +1 more source

Absent N20 of somatosensory evoked potentials and neurological outcomes after cardiac arrest: A post hoc analysis of multicenter prospective study

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
Abstract Background Somatosensory evoked potentials (SSEP) are part of the multimodal approach recommended by international guidelines for neurological prognostication after cardiac arrest (CA). Objective This study aimed to evaluate the prognostic ability of SSEP for neurological outcomes after CA.
Chie Tanaka   +4 more
wiley   +1 more source

Ginkgolide B promotes the proliferation and differentiation of neural stem cells following cerebral ischemia/reperfusion injury, both in vivo and in vitro

open access: yesNeural Regeneration Research, 2018
Neural stem cells have great potential for the development of novel therapies for nervous system diseases. However, the proliferation of endogenous neural stem cells following brain ischemia is insufficient for central nervous system self-repair ...
Pei-Dong Zheng   +5 more
doaj   +1 more source

Plasma REST: a novel candidate biomarker of Alzheimer's disease is modified by psychological intervention in an at-risk population. [PDF]

open access: yes, 2017
The repressor element 1-silencing transcription (REST) factor is a key regulator of the aging brain's stress response. It is reduced in conditions of stress and Alzheimer's disease (AD), which suggests that increasing REST may be neuroprotective.
Ashton, NJ   +9 more
core   +3 more sources

Efficacy and Safety of Butylphthalide for Neurological Recovery After Cardiac Arrest: A Pilot Randomized Controlled Trial

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Butylphthalide (NBP) is a neuroprotective agent that ameliorates cerebral ischemia‐hypoxia and reperfusion injury. However, evidence regarding whether NBP can improve neurological prognosis in patients with cardiac arrest (CA) remains limited.
Xingsheng Wang   +8 more
wiley   +1 more source

Prolonged survival in a young Dobermann with adrenal neuroblastoma

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 1‐year‐old Dobermann presented with recurrent episodes of acute diarrhoea and weight loss starting at 5 months of age. An adrenal mass was identified via ultrasound and computed tomography, leading to adrenalectomy. A diagnosis of adrenal neuroblastoma was obtained through histopathology and immunohistochemistry.
Nataliia Ignatenko   +8 more
wiley   +1 more source

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