Results 51 to 60 of about 7,357,793 (233)

THE SIGNIFICANCE OF NEURON-SPECIFIC ENOLASE LEVELS IN CEREBROSPINAL-FLUID AND SERUM AFTER EXPERIMENTAL TRAUMATIC BRAIN-DAMAGE

, 2021
In the posttraumatic period, measurement of neural tissue enzymes in serum and cerebrospinal fluid gives quantitative information about the severity of the head injury. In our study, we evaluated the relationship between the serum and cerebrospinal fluid
GUZEL, O, KAYNAR, Mehmet Yaşar, SARIOGLU, AC, OZLEN, Fatma, HANCI, Mehmet Murat, Kuday, Cengiz, UZAN, Mustafa   +6 more
core   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome [PDF]

Korean Journal of Pediatrics, 2017
PurposeThis study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children.MethodsThis prospective observational study was conducted in the pediatric ...
Dian Pratamastuti, Prastiya Indra Gunawan, Darto Saharso   +2 more
doaj   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer

Cancer Cell International, 2011
Background Neuron specific enolase (ENO2, γ-enolase) has been used as a biomarker to help identify neuroendocrine differentiation in breast cancer.
Soh Maureen A, Garrett Scott H, Somji Seema, Dunlevy Jane R, Zhou Xu, Sens Mary, Bathula Chandra S, Allen Christina, Sens Donald A   +8 more
doaj   +1 more source

Diagnostic values of glial fibrillary acidic protein, neuron-specific enolase and protein S100β for sepsis-associated encephalopathy

Romanian Journal of Laboratory Medicine, 2023
To investigate the expressions of glial fibrillary acidic protein (GFAP), neuron-specific enolase (NSE) and protein S100β and their diagnostic values for sepsis-associated encephalopathy (SAE).
Cao Zhigang, Huang Xiang, Chen Feixiang
doaj   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Neuron-specific enolase is a marker of cerebral ischemia and infarct size in rat cerebrospinal fluid.

, 1988
Neuron-specific enolase concentrations were measured in samples of rat cerebrospinal fluid obtained repeatedly before and after occlusion of the middle cerebral artery.
H G Hårdemark, Y Olsson, H G Bolander, L Persson, L Hillered, S Påhlman   +5 more
core   +1 more source

Pathogenetic Mechanisms of Brain Damage at Neuroinfections in Children

Aktualʹnaâ Infektologiâ, 2014
The article presents the value of neuron-specific enolase and autoantibodies to glutamate receptor NR2A subunits as markers of ischemia and neurodestruction at acute meningitis in children.
L.V. Pypa, R.V. Svistilnyk, T.V. Serdiuk, Yu.M. Lysytsia   +3 more
doaj   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source