Results 111 to 120 of about 7,357,793 (233)

Expression and regulation of neuron-specific enolase [PDF]

open access: yes
Neuron-specific enolase (NSE) is an isoform of the glycolytic enzyme enolase which is expressed specifically in neurons and neuroendocrine cells in the mammalian nervous system.
Twyman, Richard M.
core  

Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise in the heat and elevated tissue temperature are associated with neuronal stress and changes in blood–brain barrier (BBB) function. More severe thermal insult may manifest as exertional heat illness (EHI) and complication by central nervous system (CNS) dysfunction may persist post‐EHI.
Tom W. Palin   +15 more
wiley   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman   +2 more
wiley   +1 more source

Interference and correction of slight hemolysis in the Roche electrochemiluminescence neuron-specific enolase immunoassay

open access: yes
Neuron-specific enolase (NSE) is a key biomarker for neuroendocrine tumors and neurological injuries.
Panpan Lv   +5 more
core   +1 more source

Unraveling a Diagnostic Enigma: A TECPR2 Case Solved Through Multi‐Omic Genomics

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2338-2344, October 2026.
ABSTRACT TECPR2 is a key regulator of autophagy, encoded by the TECPR2 gene. Pathogenic variants in this gene have been linked to a rare hereditary sensory and autonomic neuropathy with intellectual disability (HSAN9). We report a teenage female with a syndromic intellectual disability disorder associated with neuromuscular abnormalities.
Teresa Zhao   +123 more
wiley   +1 more source

Cytological Features of Clear Cell Sarcoma in Exfoliative and Effusion Cytology Specimen—A Case Report and Literature Review

open access: yesDiagnostic Cytopathology, Volume 54, Issue 10, Page 731-737, October 2026.
ABSTRACT Clear cell sarcoma of soft tissue (CCSST) with malignant effusion is a rare yet clinically aggressive appearance, which may pose a diagnostic pitfall with its overlapping cytomorphologic features with metastatic melanoma and carcinoma.
William H. Wu   +2 more
wiley   +1 more source

Release of erythropoietin and neuron-specific enolase after breath holding in competing free divers

open access: yes, 2015
Free diving is associated with extreme hypoxia. This study evaluated the combined effect of maximal static breath holding and underwater swimming on plasma biomarkers of tissue hypoxemia: erythropoietin, neuron-specific enolase and S100B, C-reactive ...
Olsen, Niels Vidiendal   +5 more
core   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo   +4 more
wiley   +1 more source

Neuron Specific Enolase and Serum Electrolytes in Comatose Patients

open access: yes
Background: Coma is a profound state of unconsciousness in which the patient cannot be roused by external stimuli. The metabolic fingerprint of comatose patients is essential to identify the underlying molecular pathways and to use as a basis for ...
Beden, Murtada Wafi
core   +1 more source

Long‐Term Survival Following Nivolumab Treatment in Pulmonary Tumour Thrombotic Microangiopathy Associated With Cancer of Unknown Primary: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 10, October 2026.
Pulmonary tumour thrombotic microangiopathy (PTTM) is a rapidly fatal condition that is rarely diagnosed during life. Early clinical recognition and prompt nivolumab treatment resulted in long‐term survival in a patient with cancer of unknown primary‐associated PTTM.
Kosuke Fujishima   +4 more
wiley   +1 more source

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