Results 51 to 60 of about 33,362 (231)

Circulating Neuron-Specific Enolase in Medullary Thyroid Cancer

The International Journal of Biological Markers, 1986
The utility of determining circulating neuron-specific enolase (NSE) in medullary thyroid carcinoma was assessed in 25 patients followed up for a mean period of 45.6 months.
Furio Pacini, Rossella Elisei, Stefano Anelli, Lucia Gasperini, Ernestina Schipani, Aldo Pinchera   +5 more
doaj   +1 more source

Pathogenetic Mechanisms of Brain Damage at Neuroinfections in Children

Aktualʹnaâ Infektologiâ, 2014
The article presents the value of neuron-specific enolase and autoantibodies to glutamate receptor NR2A subunits as markers of ischemia and neurodestruction at acute meningitis in children.
L.V. Pypa, R.V. Svistilnyk, T.V. Serdiuk, Yu.M. Lysytsia   +3 more
doaj   +1 more source

Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP) [PDF]

, 2009
Background: Pro-gastrin releasing peptide ( ProGRP) concentrations in blood play an important role in the diagnosis and treatment of patients with small cell lung cancer (SCLC).
Beligere, Gangamani S., Chan, Daniel W., Chan, Sabrina S., Dowell, Barry L., Elliott, Debra, Fujita, Kenju, Hofmann, Karin, Iizuka, Masayuki, Kinukawa, Hideki, Matsuoka, Yoshiharu, Patil, Rahul D., Saegusa, Haruhisa, Sakurai, Yousuke, Scheuer, Cornelia, Sokoll, Lori, Stieber, Petra, Yamaguchi, Ken, Yoshimura, Toru   +17 more
core   +2 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

The prognostic value of neuron specific enolase in head injury

Egyptian Journal of Critical Care Medicine, 2013
Background: The development and the use of biochemical markers for assessment of brain injury severity have been of considerable interest. The most promising marker of brain damage is considered to be neuron-specific enolase (NSE); predominantly located ...
Sameh El-Maraghi, Heba Yehia, Hazem Hossam, Ahmed Yehia, Hossam Mowafy   +4 more
doaj   +1 more source

A pilot feasibility, safety and biological efficacy multicentre trial of therapeutic hypercapnia after cardiac arrest: study protocol for a randomized controlled trial [PDF]

, 2015
BACKGROUND: Cardiac arrest causes ischaemic brain injury. Arterial carbon dioxide tension (PaCO2) is a major determinant of cerebral blood flow. Thus, mild hypercapnia in the 24 h following cardiac arrest may increase cerebral blood flow and attenuate ...
Antoine G Schneider, Glenn M Eastwood, Michael Bailey, null null, Rinaldo Bellomo, Satoshi Suzuki   +5 more
core   +3 more sources

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis

Journal of the Pakistan Medical Association
The retrospective study was conducted at Baoding No.1 Central Hospital, China, and comprised data from July 2021 to January 2023, and aimed at exploring the relationship of neuron-specific enolase, D-dimer and lactate dehydrogenase with prognosis in ...
Jing Xie, Lu Zhang, Ning Gan
doaj   +1 more source

New and old biomarkers in the differential diagnosis of lung cancer: Pro-gastrin-releasing peptide in comparison with neuron-specific enolase, carcinoembryonic antigen, and CYFRA 21-1

The International Journal of Biological Markers, 2019
Background: Testing for circulating biomarkers in lung cancer is hampered by the insufficient specificity. We aimed to assess the relative diagnostic accuracy of pro-gastrin-releasing peptide (ProGRP) for the differential diagnosis of small cell lung ...
Cristian Mauro, Rita Passerini, Lorenzo Spaggiari, Domenico Galetta, Davide Radice, Paola Lentati, M. Teresa Sandri   +6 more
doaj   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source