Results 301 to 310 of about 1,209,467 (344)

Integrating with Neurons

Annual Review of Neuroscience, 1989
says that y is the time integral of x. This mathematical operation occurs in the central nervous system and is the subject of this review. The review concentrates on the integrator of the vestibulo-ocular reflex as a prominent example, offers a model of how integration might be done by neurons, and speculates about the extent to which neural ...
openaire   +3 more sources

Neuron-to-Neuron Transmission of Neurodegenerative Pathology

The Neuroscientist, 2013
One of the hallmarks of neurodegenerative dementia diseases is the progressive loss of mental functions and the ability to manage activities of daily life. This progression is caused by the spread of the disease to more and more brain areas via anatomical connections.
Jan Marcusson, Martin Hallbeck, Sangeeta Nath   +2 more
openaire   +3 more sources

Alzheimer’s pathogenesis: is there neuron-to-neuron propagation?

Acta Neuropathologica, 2011
There is increasing interest in the early phase of Alzheimer's disease before severe neuronal dysfunction occurs, but it is still not known when or where in the central nervous system the underlying pathological process begins. In this review, we discuss the idea of possible disease progression from the locus coeruleus to the transentorhinal region of ...
Heiko Braak, Kelly Del Tredici
openaire   +3 more sources

Neuronal Markers in Non-Neuronal Tissues

2007
Many proteins first identified in the nervous system were also found to be expressed elsewhere in the body. The text reviews some of these 'neuronal' markers and delineates intersections between nervous and non-nervous tissues on the structural and functional level.
Christian Hagel, Dimitrios Stavrou
openaire   +3 more sources

The neuron doctrine is an insult to neurons

Behavioral and Brain Sciences, 1999
As presently implemented, the neuron doctrine (ND) portrays the brain's neurons and chemical synapses as fundamental components in a computer-like switching circuit, supporting a view of brain = mind = computer. However, close examination reveals individual neurons to be far more complex than simple switches, with enormous capacity for ...
openaire   +2 more sources

Neuronal Targeting in Diabetes Mellitus: A Story of Sensory Neurons and Motor Neurons

The Neuroscientist, 2008
Diabetes mellitus targets the peripheral nervous system in unique but disabling ways. Although several mechanisms may target peripheral neurons, they render a degenerative pattern of damage that begins in distal terminals. Moreover, sensory neurons are involved early, motor neurons later.
Cory Toth, Noor Ramji, Douglas W. Zochodne   +2 more
openaire   +3 more sources

Neuronal Communication: Cooperativity of unreliable neurons

Current Biology, 1994
Recent studies show that many presynaptic neurons must cooperate to generate a postsynaptic output, though the number is still just a tiny fraction of all the postsynaptic cell's inputs.
openaire   +3 more sources

Neurons and Neuronal Signal Propagation

2002
The human brain contains approximately 1012 to 1013 cells. About 1011 cells out of this pool can be classified as nerve cells or neurons. Although representing only 2–10 % of all brain cells, it is widely accepted that the neurons and their mutual synaptic connections form the anatomical subsfrate for die powerful computational abilities of the brain ...
openaire   +2 more sources

P-neuron: a neuron with a center

[Proceedings] 1991 IEEE International Joint Conference on Neural Networks, 1991
A neuron widely used for learning is based on an inner product of a weight vector and an input vector and a threshold function, which represents a step-like surface in a hyperspace. The proposed neuron decides the position and sharpness of the step by three parameters: the normal vector, the center position vector, and the sharpness.
openaire   +2 more sources

" NEURON " OR " NEURONE " ?

The Lancet, 1963
openaire   +5 more sources