Results 191 to 200 of about 7,357,818 (235)

Clinical biochemistry of neuron specific enolase

Clinica Chimica Acta, 1989
The soluble brain protein 14-3-2 first described by Moore and McGregor in 1965 is now known to be a cell specific isoenzyme of the glycolytic enzyme enolase (EC 4.2.1.11), designated neuron specific enolase (NSE). It is not only a marker for all types of neurons, but also for all neuroendocrine or paraneuronal cells.
E, Kaiser, R, Kuzmits, P, Pregant, O, Burghuber, W, Worofka   +4 more
openaire   +2 more sources

Phylogenetic Distribution of Neuron‐Specific Enolase

Journal of Neurochemistry, 1980
Abstract: Neurons and neuroendocrine cells contain a unique isoenzyme of the glycolytic enzyme enolase which is not found in other cells. This acidic enolase isoenzyme has been designated neuron specific enolase or NSE and is easily identified by its elution on DEAE sephadex.
R L, Clark-Rosenberg, P J, Marangos
openaire   +2 more sources

Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation

Brain Research, 1980
The enolase (EC 4.2.1.11) isoenzymes, neuron-specific enolase (NSE, gamma gamma) and non-neuronal enolase (NNE, alpha alpha), are markers for neurons and glia, respectively, in adult mammalian brain. In developing fetal and early postnatal brain, levels of non-neuronal enolase (NNE) are high.
D E, Schmechel, M W, Brightman, P J, Marangos   +2 more
openaire   +2 more sources

Neuron‐specific enolase levels in primary cultures of neurons

Journal of Neuroscience Research, 1980
AbstractPrimary neuronal cell cultures, derived by centrifugal elutriation of cells dissociated from embryonic rat cerebra, have been analyzed for their content of neuron‐specific enolase (NSE) and non‐neuronal enolase (NNE). Both immunocytochemical staining and radioimmunoassay establish that NSE is present in these cells.
C L, Schengrund, P J, Marangos
openaire   +2 more sources

Neuron Specific Enolase

Scandinavian Journal of Clinical and Laboratory Investigation, 1988
(1988). Neuron Specific Enolase. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 48, No. sup190, pp. 49-49.
openaire   +1 more source

Neuron-Specific Enolase as a Marker of in Vitro Neuronal Damage. Part I: Assessment of Neuron-Specific Enolase as a Quantitative and Specific Marker of Neuronal Damage

Journal of Neurosurgical Anesthesiology, 1993
Enolase in cerebrospinal fluid is a sensitive marker for many types of neurological injuries including head injury and ischemia. We assessed neuron-specific enolase (NSE) as a quantitative and specific biochemical marker of neuronal damage in an experimental model of kainate neurotoxicity.
Hans, Pol, Bonhomme, Vincent, Collette, Julien, Moonen, Gustave   +3 more
openaire   +3 more sources

Neuron‐specific enolase in retinoblastoma

Acta Ophthalmologica, 1986
Abstract Forty‐six retinoblastoma specimens were studied for the presence of neuron‐specific enolase (NSE) in the tumour cells and in the remaining morphologically normal retina. The laboratory method was a sensitive immunohistochemical peroxidase staining procedure, and normal ocular nerves were used as positive controls.
openaire   +2 more sources

Neuron Specific Enolase

1995
Enolase is a dimeric glycolytic enzyme which exists in four natural isomeric forms. The α-α is widely distributed through many tissues, whilst the α-γ and the γ-γ forms are restricted to neural and neuroendocrine tissues. The β-β form is present in skeletal muscle.
openaire   +1 more source

Localisation of neurone-specific enolase (ENO2) to 12p13

Cytogenetics and Cell Genetics, 2008
We have localised the human cDNA for neurone-specific enolase (EN02) to chromosome region 12p13 by in situ hybridisation. Two additional smaller peaks of hybridisation to specific chromosomal subregions were observed. That on chromosome lp36 probably represents cross-hybridisation to the locus for nonneuronal enolase (ENOl), which has been previously ...
S P, Craig, I N, Day, R J, Thompson, I W, Craig   +3 more
openaire   +2 more sources

The structure and expression of neuron-specific enolase gene

Gene, 1987
Neuron-specific (gamma gamma) enolase (NSE) is an isoenzyme form of glycolytic enzyme, enolase. We isolated genomic clones for NSE and clarified NSE gene structures. The NSE-gene spanned about 9 kb and consisted of twelve exons and eleven introns. Multiple transcriptional start points were identified by a combination of S1 nuclease mapping and primer ...
K, Sakimura, E, Kushiya, Y, Takahashi, Y, Suzuki   +3 more
openaire   +2 more sources