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Differential effects of SOCS2 on neuronal differentiation and morphology
Brain Research, 2006Neuronal differentiation of neural progenitor cells is regulated by a variety of growth and transcription factors, that not only regulate cell fate of the progenitor cells but that can also regulate neuronal morphology. Suppressor of cytokine signaling-2 (SOCS2) is an intracellular regulator of Growth Hormone (GH) signaling that is expressed in neural ...
Hannah J, Scott +6 more
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Immunocytochemical Analysis of Neuronal Differentiation
2003Fully understanding the phenotype of neurons in vivo involves examining their morphology, immunocytochemically analyzing their protein expression, examining their afferent and efferent integration into neuronal microcircuitry, and functionally examining their activity.
Sanjay S P, Magavi, Jeffrey D, Macklis
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Differentiation of neuronal from non-neuronal Substance P
Regulatory Peptides, 2009Substance P (SP) originally found as a neuropeptide in capsaicin-sensitive sensory neurons, had more recently been identified in non-neuronal cells, especially under pathological conditions. Neuronal and non-neuronal SP may perform distinct functions. A simple technique to differentiate different SP sources is currently unavailable. Herein, we describe
Nuray, Erin, Ozkan, Ulusoy
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Foxp2 regulates neuronal differentiation and neuronal subtype specification
Developmental Neurobiology, 2014ABSTRACTMutations of the transcription factor FOXP2 in humans cause a severe speech and language disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or ultrasonic vocalization, respectively. These data suggest that Foxp2 plays important roles in the developing nervous system.
Yi-Chi, Chiu +5 more
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Differentiation of Cochlear Afferent Neurons
Acta Oto-Laryngologica, 1981In order to clarify some open questions, the various types of afferent neurons of the cochlea were analysed in various species regarding their structural features, their association with outer or inner hair cells and their connection to the CNS, by means of degeneration experiments and tracer studies.
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How Not to Differentiate a Neuron
Science's STKE, 2005What do neuronal precursor cells and non-neuronal cells have in common? Neither expresses the genes typical of differentiated neurons. Yeo et al. now show what else is in common: expression of certain SCP phosphatases.
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Drosophila Neuron Differentiation in Vitro
1971Many investigators have described the growth of axons in vitro from explants of embryonic mammalian or bird tissue (Murray, 1965). In all cases the explant contained cells from already differentiated nervous tissue and no claims were made for neuron differentiation from stem cells.
R L, Seecof, R L, Teplitz
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Concanavalin a binding and neuronal differentiation
Virchows Archiv A Pathological Anatomy and Histopathology, 1984Concanavalin A (Con A) acceptors have been demonstrated in large differentiated neurons in a previous paper. In order to elucidate the correlation between Con A binding in normal and neoplastic neurons and lectin binding dependence upon the differentiation grade, 26 tumours of the neuronal series were examined using formalin fixed and paraffin embedded
K, Schwechheimer, G, Weiss, P, Möller
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Platelet preparations in neuronal cell differentiation
Italian Journal of Anatomy and Embryology, 2017Concentrated Growth Factors (CGF) is a platelet rich preparation that has the important feature of a tight fibrin network and containing a large number of growth factors possessing great regenerative potentialities [1]. The regeneration of nervous system is one of the mail goal of regenerative medicine. The aim of this study is to test the in vitro CGF
Bonazza V +7 more
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The effect of neuronal cells on kidney differentiation
The International Journal of Developmental Biology, 1989During embryonic growth, tissue interactions between dissimilar cells are the driving forces of morphogenesis. Although their importance has been well known for over the past 50 years, the molecular background of these interactions has remained unelucidated.
Sariola, H. +2 more
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