Results 111 to 120 of about 2,225,985 (280)

Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral Cortex [PDF]

, 2017
The migration of neuronal cells in the developing cerebral cortex is essential for proper development of the brain and brain networks. Disturbances in this process, due to genetic abnormalities or exogenous factors, leads to aberrant brain formation ...
Leonards, Pim E G; id_orcid, Jan Wijnholds, Wijnholds, J., Dudok, Jacobus J; id_orcid, Wijnholds, Jan, Pim Leonards, Jacobus Dudok, Dudok, J.J., Leonards, P.E.G.   +8 more
core   +1 more source

Cathepsin B deficiency disrupts cortical development via PEG3, leading to depression-like behavior

Communications Biology
Cathepsin B (CatB), a protease in endosomal and lysosomal compartments, plays a key role in neuronal protein processing and degradation, but its function in brain development remains unclear.
Zhen Xie, Qinghu Yang, Fei Lan, Wei Kong, Shuxuan Zhao, Jinyi Sun, Yan Yan, Zhenzhen Quan, Zhantao Bai, Hong Qing, Jian Mao, Junjun Ni   +11 more
doaj   +1 more source

Functional role of a glycolipid in directional movements of neurons

Anais da Academia Brasileira de Ciências, 2001
Migration of neurons from their site of origin to their final destination is a critical and universal step in the formation of the complex structure of the nervous system.
ROSALIA MENDEZ-OTERO, MARCELO F. SANTIAGO   +1 more
doaj   +1 more source

Role of Structural Disorder on Phonon Transport and Thermal Conductivity in Li6PS5Br

Advanced Functional Materials, EarlyView.
Solid electrolytes are fast ion and slow heat conductors. Although both transport properties are governed by lattice dynamics and atomic structure, their interplay remains poorly understood. Here, we study this interrelation in anion‐ordered and disordered Li6PS5Br.
Lukas Ketter, Ryoma Sasaki, Kyra Strotmann, Wolfgang G. Zeier, Yoshitaka Tateyama   +4 more
wiley   +1 more source

Myosin X Regulates Neuronal Radial Migration through Interacting with N-cadherin

Frontiers in Cellular Neuroscience, 2015
Proper brain function depends on correct neuronal migration during development, which is known to be regulated by cytoskeletal dynamics and cell-cell adhesion.
Mingming eLai, Mingming eLai, Ye eGuo, Jun eMa, Huali eYu, Dongdong eZhao, Wenqiang eFan, Xingda eJu, Muhammad Abid Sheikh, Yousra Saeed Malik, Wencheng eXiong, Weixiang eGuo, Xiaojuan eZhu   +12 more
doaj   +1 more source

Configuration‐Encoded Cell Alignment by Light‐Gated Silicon Photovoltaic Microcell Arrays

Advanced Functional Materials, EarlyView.
Light‐gated silicon photovoltaic microcells convert pulsed illumination into localized electrical cues. Arranging otherwise similar microcells into four‐lobed, six‐lobed, or circular patterns directs fibroblasts into corresponding local arrangements without wired stimulation.
Yifan Tao, Ilayda Namli, Joseph Christakiran Moses, Youdi Liu, Suihong Liu, Syed Hasan Askari Rizvi, Yasar Ozer Yilmaz, Ibrahim T. Ozbolat   +7 more
wiley   +1 more source

The F-BAR Domain of srGAP2 Induces Membrane Protrusions Required for Neuronal Migration and Morphogenesis [PDF]

, 2009
SummaryDuring brain development, proper neuronal migration and morphogenesis is critical for the establishment of functional neural circuits. Here we report that srGAP2 negatively regulates neuronal migration and induces neurite outgrowth and branching ...
Chen, Keng, Guerrier, Sabrice, Sassa, Takayuki, Jin, Wei Lin, Jordan, Nicole Vincent, Coutinho-Budd, Jaeda, Polleux, Franck, Gresset, Aurélie, Frost, Adam   +8 more
core   +1 more source

Programming Neuromorphic Plasticity Through Ionic and Electronic Coupling in Organic Electrochemical Transistors

Advanced Functional Materials, EarlyView.
Neuromorphic plasticity in OECTs is governed by the post‐stimulus evolution of coupled ionic and electronic states. Semiconductor chemistry and morphology, electrolyte composition and interfaces, and device architecture regulate ion injection, transport, confinement, and release, shifting responses from rapidly relaxing STP to metastable memory and ...
Inho Lee, Hyoik Jang, Ji Hwan Kim, Jonghyun Won, Namhee Kim, Wonseok Shin, Giwon Lee, Eunho Lee, Daegun Kim, Sungjun Park   +9 more
wiley   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source