Psychedelic compounds directly excite 5-HT<sub>2A</sub> layer V medial prefrontal cortex neurons through 5-HT<sub>2A</sub> Gq activation. [PDF]
Schmitz GP +10 more
europepmc +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
Dysfunction of the rostral lateral septum GABAergic neurons induces mania-like behavior in male mice. [PDF]
Zhou Y +8 more
europepmc +1 more source
Workflow of the parameter optimization process for ITSC fault detection, applying Differential Evolution optimization and the Smooth Pseudo Wigner‐Ville Distribution for signal processing. The optimized parameters are then used in the failure identification pipeline, which combines the signal processing with a YOLO‐based architecture for fault severity
Rafael Martini Silva +4 more
wiley +1 more source
The involvement of 5-HT was necessary for EA-mediated improvement of post-stroke depression. [PDF]
Deng B +11 more
europepmc +1 more source
Data‐Driven Distributed Safe Control Design for Multi‐Agent Systems
This paper presents a data‐driven control barrier function (CBF) technique for ensuring safe control of multi‐agent systems (MASs) with uncertain linear dynamics. A data‐driven quadratic programming (QP) optimization is first developed for CBF‐based safe control of single‐agent systems using a nonlinear controller. This approach is then extended to the
Marjan Khaledi, Bahare Kiumarsi
wiley +1 more source
A frugal Spiking Neural Network for unsupervised multivariate temporal pattern classification and multichannel spike sorting. [PDF]
Pokala SD +5 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Neuronal Damage Induced by Gradual Oxidative Stress in iPSC-Derived Neurons: Implications for Ferroptosis Involvement and ALS Drug Evaluation. [PDF]
Kobayashi H +4 more
europepmc +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source

