Results 281 to 290 of about 1,969,205 (328)

VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior. [PDF]

Nat Commun
Barbano MF, Wang H, Zhang S, Shevelkin AV, Yu KJ, Richie CT, Liu B, Hahn S, Ye R, Morales M.   +9 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Neural mechanism of HT7 electroacupuncture in myocardial ischemia: critical role of the paraventricular nucleus oxytocin system. [PDF]

Front Neurosci
Wu HS, Zhu L, Liu P, Liu XH, Su H, Zheng XY, Liu TT, Cui S, Wu SB, Zhou MQ, Zhu C.   +10 more
europepmc   +1 more source

Detecting Dengue in Flight: Leveraging Machine Learning to Analyze Mosquito Flight Patterns for Infection Detection

Advanced Biology, EarlyView.
Dengue infection alters mosquito flight behavior, enabling detection using machine learning classifiers. This study analyzes 3D flight trajectories and evaluates multiple models, showing that longer sequence lengths improve classification performance.
Nouman Javed, Adam J. López‐Denman, Prasad N. Paradkar, Asim Bhatti   +3 more
wiley   +1 more source

GABA_B receptor-mediated potentiation of ventral medial habenula glutamatergic transmission in GABAergic and glutamatergic interpeduncular nucleus neurons. [PDF]

IBRO Neurosci Rep
Stinson HE, Ninan I.
europepmc   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuela Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source

Identification of VGLUT3-expressing LTMRs-recruited spinal circuits for itch inhibition. [PDF]

Mol Brain
Su X, Wang L, Liu X, Zhang Y.
europepmc   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Circuit-level modeling of prediction error computation of multi-dimensional features in voluntary actions. [PDF]

Front Comput Neurosci
Huang Y, Li Y.
europepmc   +1 more source