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Neurons but Motor Neurons in Motor Neuron disease

2014
The occurrence of motor neuron death is the milestone of amyotrophic lateral sclerosis (ALS). Therefore, morphological analysis along decades focussed on motor neuron loss as the sole marker to score disease severity. Recently, non autonomous cell death took a prominent role to explain the need for additional cell types to induce motor neuron ...
Fornai, Francesco   +8 more
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Imprinting in neuron

Neuroscience Research, 2006
Although most imprinted genes display parent-origin-specific gene expression in tissues where they are transcribed, some genes are imprinted in a tissue-specific manner. Genes that show brain-specific imprinting or brain-specific lack of imprinting present a unique opportunity to study the process of imprinting during tissue differentiation.
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Neuronal Markers in Non-Neuronal Tissues

2007
Many proteins first identified in the nervous system were also found to be expressed elsewhere in the body. The text reviews some of these 'neuronal' markers and delineates intersections between nervous and non-nervous tissues on the structural and functional level.
Christian, Hagel, Dimitrios, Stavrou
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miRNA and Neurons

International Journal of Neuroscience, 2009
Micro RNAs (miRNAs) are endogenous noncoding RNAs that are important for gene regulation. This review provides an overview of miRNA biogenesis and mechanism of action. The review focuses on studies relating to the spatial and temporal regulation of gene expression in neurons.
S, Trivedi, G, Ramakrishna
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A silicon neuron

Nature, 1991
By combining neurophysiological principles with silicon engineering, we have produced an analog integrated circuit with the functional characteristics of real nerve cells. Because the physics underlying the conductivity of silicon devices and biological membranes is similar, the 'silicon neuron' is able to emulate efficiently the ion currents that ...
Mahowald, Misha, Douglas, Rodney
openaire   +3 more sources

Neuronal Communication: Cooperativity of unreliable neurons

Current Biology, 1994
Recent studies show that many presynaptic neurons must cooperate to generate a postsynaptic output, though the number is still just a tiny fraction of all the postsynaptic cell's inputs.
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Dopaminergic neurons

The International Journal of Biochemistry & Cell Biology, 2005
Dopaminergic neurons of the midbrain are the main source of dopamine (DA) in the mammalian central nervous system. Their loss is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons are found in a 'harsh' region of the brain, the substantia nigra pars compacta, which is DA-rich and ...
Shankar J, Chinta, Julie K, Andersen
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Neuronal assemblies

IEEE Transactions on Biomedical Engineering, 1989
This paper examines the concept of neuronal assembly as it has appeared in selected portions of the literature. The context is experimental access to real neuronal assemblies in working brains, as made possible by recent technological progress. One current measure of assembly organization is based on correlation of firing among neurons; recent ...
Gerstein, G.   +2 more
openaire   +3 more sources

Neuronal beacon

Optics Letters, 2013
The controlled navigation of the axonal growth cone of a neuron toward the dendrite of its synaptic partner neuron is the fundamental process in forming neuronal circuitry. While a number of technologies have been pursued for axonal guidance over the past decades, they are either invasive or not controllable with high spatial and temporal resolution ...
B, Black   +3 more
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Artificial Neuron

Science, 1959
An electronic model is described for simulating many of the gross operational functions which are believed to hold for living nerve cells. Synaptic growth is not included. Despite difficulties in drawing very rigorous analogies between the biological cell and its model, a sufficient number of rough similarities exist to make systemic experimentation ...
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