Results 321 to 330 of about 2,597,556 (387)
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Simple model of spiking neurons

IEEE Trans. Neural Networks, 2003
A model is presented that reproduces spiking and bursting behavior of known types of cortical neurons. The model combines the biologically plausibility of Hodgkin-Huxley-type dynamics and the computational efficiency of integrate-and-fire neurons.
E. Izhikevich
semanticscholar   +1 more source

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.

Science, 1992
Neurogenesis in the mammalian central nervous system is believed to end in the period just after birth; in the mouse striatum no new neurons are produced after the first few days after birth.
B. Reynolds, S. Weiss
semanticscholar   +1 more source

Development of neuron–neuron synapses

Current Opinion in Neurobiology, 2000
Our understanding of neuronal synapse development has advanced in recent years. The development of glycinergic synapses appears to depend on gephyrin and glycine receptor activity. Molecular characterization of the structure and development of glutamatergic synapses is in progress, but the underlying mechanisms remain unclear.
Sang Hyoung Lee, Morgan Sheng
openaire   +2 more sources

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.

Science, 1993
A potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons was purified and cloned. Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the ...
L.-F. H. Lin   +4 more
semanticscholar   +1 more source

From Neurons to Neighborhoods: The Science of Early Childhood Development

, 2000
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the ...
J. Shonkoff, D. Phillips
semanticscholar   +1 more source

Ischemic cell death in brain neurons.

Physiological Reviews, 1999
This review is directed at understanding how neuronal death occurs in two distinct insults, global ischemia and focal ischemia. These are the two principal rodent models for human disease.
P. Lipton
semanticscholar   +1 more source

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain.

Science, 1982
Recent evidence indicates that the nucleus basalis of Meynert, a distinct population of basal forebrain neurons, is a major source of cholinergic innervation of the cerebral cortex.
P. Whitehouse   +5 more
semanticscholar   +1 more source

D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.

Science, 1990
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the substantia nigra. Severe movement disorders result from the loss of striatal dopamine in patients with Parkinson's disease ...
C. Gerfen   +6 more
semanticscholar   +1 more source

EvOL-Neuron: Neuronal morphology generation

Neurocomputing, 2008
Virtual neurons are essential in computational neuroscience to study the relation between neuronal form and function. One way of obtaining virtual neurons is by algorithmic generation from scratch. However, a main disadvantage of current available generation methods is that they impose a priori limitations on the outcomes of the algorithms.
Eric O. Postma   +2 more
openaire   +3 more sources

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