Results 91 to 100 of about 97,051 (285)
Epilepsia, EarlyView.Abstract Brain development and subsequent brain function are highly sensitive to genetic mutations, which can result in severe neurodevelopmental malformations. Alterations in PTEN signaling cause a spectrum of developmental malformations and neurological diseases including epilepsy.
Franziska Fazekas +16 more
wiley +1 more source
Imipramine treatment reduces Alzheimer’s disease neuropathologies in cerebral organoid models of Alzheimer’s disease and Down syndrome [PDF]
, 2023 Noah R. Johnson +4 more
openalex +1 more source
Epilepsia, EarlyView.Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras +6 more
wiley +1 more source
Analysis of the intestinal microbiota and its relationship with neuropathologies
, 2023 Carlos Alexandre Gomes Passarinho Menezes +11 more
openalex +1 more source
Epilepsia, EarlyView.Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury +7 more
wiley +1 more source
An algorithm for seizure detection in rodents
Epilepsia Open, EarlyView.Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky +9 more
wiley +1 more source
PathogensZika virus (ZIKV) is a reemerging flavivirus that is primarily spread through bites from infected mosquitos. It was first discovered in 1947 in sentinel monkeys in Uganda and has since been the cause of several outbreaks, primarily in tropical and ...
Kenneth C. Elliott +1 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen +24 more
wiley +1 more source
Miro GTPases at the Crossroads of Cytoskeletal Dynamics and Mitochondrial Trafficking
CellsMiro GTPases are key components in the machinery responsible for transporting mitochondria and peroxisomes along microtubules, and also play important roles in regulating calcium homeostasis and organizing contact sites between mitochondria and the ...
Pontus Aspenström
doaj +1 more source