Results 91 to 100 of about 423,580 (268)
Learning the Parameters of Determinantal Point Process Kernels [PDF]
arXiv, 2014 Determinantal point processes (DPPs) are well-suited for modeling repulsion and have proven useful in many applications where diversity is desired. While DPPs have many appealing properties, such as efficient sampling, learning the parameters of a DPP is still considered a difficult problem due to the non-convex nature of the likelihood function.
arxiv
Reduced vitamin D levels in painful diabetic peripheral neuropathy
Diabetic Medicine, 2018 Recent studies have reported an association between low vitamin D levels and diabetic peripheral neuropathy. However, many of these did not differentiate between people with painful diabetic peripheral neuropathy and those with painless diabetic ...
P. Shillo +7 more
semanticscholar +1 more source
Phosphorylation State of ZFP24 Controls Oligodendrocyte Differentiation
Cell Reports, 2018 Summary: Zinc finger protein ZFP24, formerly known as ZFP191, is essential for oligodendrocyte maturation and CNS myelination. Nevertheless, the mechanism by which ZFP24 controls these processes is unknown.
Benayahu Elbaz +6 more
doaj
A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
iScience, 2023 Summary: Diabetic peripheral neuropathy (DPN) is the most common chronic, progressive complication of diabetes mellitus. The main symptom is sensory loss; the molecular mechanisms are not fully understood.
Mari Suzuki +7 more
doaj
PLoS ONE, 2017 Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible technique that quantifies small nerve fibres. We have compared the diagnostic capability of CCM against a range of established measures of nerve damage in patients with ...
U. Alam +10 more
semanticscholar +1 more source
The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS
Neurobiology of Disease, 2019 Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, characterized by motor neuron death in the brain and spinal cord.
Yulia Dzhashiashvili +4 more
doaj
Journal of the American Medical Association (JAMA), 2013 IMPORTANCE There are no known effective treatments for painful chemotherapy-induced peripheral neuropathy. OBJECTIVE To determine the effect of duloxetine, 60 mg daily, on average pain severity. DESIGN, SETTING, AND PATIENTS Randomized, double-blind,
E. Smith +11 more
semanticscholar +1 more source
Efficient Estimation and Evaluation of Prediction Rules in Semi-Supervised Settings under Stratified Sampling [PDF]
arXiv, 2020 In many contemporary applications, large amounts of unlabeled data are readily available while labeled examples are limited. There has been substantial interest in semi-supervised learning (SSL) which aims to leverage unlabeled data to improve estimation or prediction.
arxiv
p62/sequestosome-1 as a severity-reflecting plasma biomarker in Charcot–Marie–Tooth disease type 1A
Scientific ReportsAutophagy is a self-degradation system for recycling to maintain homeostasis. p62/sequestosome-1 (p62) is an autophagy receptor that accumulates in neuroglia in neurodegenerative diseases.
Byeol-A Yoon +10 more
doaj +1 more source
PRIMARY SENSORY NEUROPATHY WITH MUSCULAR CHANGES ASSOCIATED WITH CARCINOMA [PDF]
, 1948 D. Denny‐Brown
openalex +1 more source