Results 141 to 150 of about 74,318 (299)

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Pro-neuropeptide Y as a circulating biomarker for poor prognosis in prostate cancer. [PDF]

Sci Rep
Djusberg E, Lundquist K, Lundholm M, Josefsson A, Karlsson CT, Schwenk JM, Brattsand M, Bergh A, Wikström P.   +8 more
europepmc   +1 more source

Neuropeptide Y Y(1) receptor regulates protein turnover and constitutive gene expression in hypertrophying cardiomyocytes.

, 2002
Increased levels of neuropeptide Y correlate with severity of left ventricular hypertrophy in vivo. At cardiomyocyte level, hypertrophy is characterised by increased mass and altered phenotype.
Nicholl, S.M., Bell, David, McDermott, Barbara, Kelso, Elizabeth   +3 more
core  

Cortical‐Hypothalamic Assembloids Uncover the Cortical Regulation of Hypothalamic Responses to Fatty Acid

Cell Proliferation, EarlyView.
By assembling cortical‐hypothalamic circuits, we show that cortical input protects hypothalamic neurons from fatty acid‐induced damage, which activates PGC1α to boost mitochondrial function. This reveals a cortico‐hypothalamic axis that defends against metabolic stress.
Mengdan Tao, Xiaowen Du, Qi Chen, Wenxin Mu, Shuning Lou, Xu Zhang, Min Xu, Jiting Li, Yuxuan Guo, Wanying Zhu, Yan Liu   +10 more
wiley   +1 more source

Age-dependent increase in peripheral neuropeptide Y with no cross-sectional link to depression. [PDF]

Acta Neuropsychiatr
Dahlaki M, Alam MDZ, Nyholm Nielsen M, Nørmølle Buttenschon H, Winterdahl M.   +4 more
europepmc   +1 more source

NPY Levels In Type 1 Diabetic Men of Different Duration.

, 2011
Background: The aim of the present study was to evaluate whether the different duration of type 1 diabetes mellitus influences basal NPY secretion. Design: The NPY concentrations were measured in sixty-eight men with insulin-dependent diabetes mellitus ...
Lavinia Volpi, Anna Araldi, Maria Grazia Magotti, Paolo Chiodera, Riccardo Volpi, Luigi Capretti, Claudio Giumelli, Vittorio Coiro, Simona Cataldo, Teore Ferri, Roberta Minelli   +10 more
core  

pH-dependent structural dynamics of neuropeptide Y in aqueous solution. [PDF]

PLoS One
Nguyen HT, Spehr M, Bondar AN, Carloni P.   +3 more
europepmc   +1 more source

Study of the interactions between the neuropeptide Y4 receptor and the intracellular proteins arrestin-2 and arrestin-3

reservedG protein-coupled receptors (GPCRs) are essential components in cellular communication. As a part of this receptor family, the neuropeptide Y receptor family plays a pivotal role in appetite, metabolism, anxiety and cancer.
PRADELLA, MATTEO
core  

Diabetic Corneal Neuropathy as a Window Into Diabetic Foot Risk: A Large‐Scale Association Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between diabetic corneal neuropathy and diabetic foot risk by examining corneal nerve features, clinical characteristics, and tear mediators in patients with different diabetic foot risk categories. Methods In this cross‐sectional study, 710 participants underwent diabetic foot examination, in vivo confocal ...
Chang Liu, Mingyi Yu, Isabelle Xin Yu Lee, Gavin Patrick O'Donnell, Hong Chang Tan, Aya Takahashi‐Nakajima, Yixin Wang, Mui Hui Koh, Ho Sean Matthew Chung‐Hei, Hasika Wickrama Senevirathne, Hla Myint Htoon, Ching‐Yu Cheng, Yu‐Chi Liu   +12 more
wiley   +1 more source

Stabilized thioamide peptide agonists of the neuropeptide Y type 2 receptor for targeted cancer imaging. [PDF]

RSC Chem Biol
Phan HAT, Chang Y, Barrett TM, Fiore KE, Zhang DY, Grove EJ, Petersson EJ.   +6 more
europepmc   +1 more source