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Neuropeptide Y and Sympathetic Neurotransmissiona
Annals of the New York Academy of Sciences, 1990The coexistence of neuropeptide Y (NPY) with noradrenaline (NA) in perivascular nerves as well as in sympathetic nerves to muscle in the heart, spleen and vas deferens suggests a role for NPY in autonomic transmission. Sympathetic nerve stimulation or reflexogenic activation in experimental animals or man are associated with NPY release as revealed by ...
Anders Franco-Cereceda +3 more
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Neuropeptide Y receptor subtypes
Life Sciences, 1995Neuropeptide Y (NPY) is an amidated 36-amino acid peptide with a wide distribution in the central and peripheral nervous system. It can evoke numerous physiological responses by activating specific receptors. Studies using NPY analogs in various model systems and cell types demonstrate different orders of ligand potency and receptor binding affinity ...
Chok P. Wan, Benjamin H.S. Lau
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Neuropeptide Y and the cerebral circulation
2006The presence of NPY receptors on both endothelial and vascular smooth muscle cells indicates that blood-borne NPY as well as NPY stemming from surrounding nerves can affect contractile responses of cerebral vessels. In addition, endothelial cells may themselves be a source of NPY as well as a site of NPY metabolism.
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Neuropeptide Y: the universal soldier
Cellular and Molecular Life Sciences CMLS, 2003The peptidic neuropeptide Y (NPY) has received great attention because it has been implicated in the regulation of several organ systems. In particular, NPY is involved in the regulatory loops that control food intake in the hypothalamus and appears also to be important for regulating the activity of neuroendocrine axes under poor metabolic conditions.
Eric Grouzmann +2 more
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NEUROPEPTIDE Y AND CARDIOVASCULAR REGULATION
Clinical and Experimental Pharmacology and Physiology, 1991SUMMARY1. The effects of neuropeptide Y (NPY) and related peptide fragments on blood pressure and vagal action at the heart were compared in the anaesthetized rat.2. A change in vagal action was taken as a measure of presynaptic activity and a change in blood pressure was taken as a measure of postsynaptic activity.3.
D I McCloskey, Erica K. Potter
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2000
Part I. Cloning Techniques. Cloning Neuropeptide Tyrosine cDNA, Carolyn A. Worby. Human Y1/Y5 Receptor Gene Cluster: Isolation and Characterization, Herbert Herzog. Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization, David A. Ammar and Debra A. Thompson.
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Part I. Cloning Techniques. Cloning Neuropeptide Tyrosine cDNA, Carolyn A. Worby. Human Y1/Y5 Receptor Gene Cluster: Isolation and Characterization, Herbert Herzog. Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization, David A. Ammar and Debra A. Thompson.
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2004
Neuropeptide Y (NPY) is a co-transmitter of the sympathetic nervous system including the renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide YY (PYY), a circulating hormone released from gastrointestinal cells. Five subtypes of NPY receptors have been cloned, among which Y1, Y2and Y5 appear to be involved in the ...
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Neuropeptide Y (NPY) is a co-transmitter of the sympathetic nervous system including the renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide YY (PYY), a circulating hormone released from gastrointestinal cells. Five subtypes of NPY receptors have been cloned, among which Y1, Y2and Y5 appear to be involved in the ...
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Neuropeptide Y and Limbic Seizures
Reviews in the Neurosciences, 1998Since its discovery in 1982, neuropeptide Y (NPY), a 36 amino-acid member of the pancreatic polypeptide family, has received considerable attention in the field of neuroscience. Originally isolated from porcine brain /86/, NPY is one of the most abundant and widely distributed peptides in the central nervous system.
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Neuropeptide Y in the dentate gyrus
2007Neuropeptide Y (NPY) is contained in at least four types of GABAergic interneurons in the dentate gyrus, many of which also contain somatostatin and give rise to the dense NPY innervation of the dentate outer molecular layer. In humans but not rats, minute amounts of NPY are also normally expressed in dentate granule cells, while seizure activity in ...
William F. Colmers +2 more
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