Results 131 to 140 of about 33,315 (302)

Associations of Monocyte Glucocerebrosidase with Cognition and Cholinergic Innervation in GBA1 Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background The GBA1 gene encodes the lysosomal enzyme glucocerebrosidase (GCase). Parkinson's disease (PD) patients carrying a GBA1 variant (GBA‐PD) exhibit faster cognitive decline, linked to cholinergic degeneration. Objectives The aim was to investigate whether GCase activity, measured in monocytes, correlates with cognitive dysfunction or ...
Sofie Slingerland, Sygrid van der Zee, Sven C.D. van Ijzendoorn, Anne C. Slomp, Jeffrey M. Boertien, Sanne K. Meles, Arjan Kol, Marie Geerlings, Teus van Laar   +8 more
wiley   +1 more source

Electroencephalography‐Based Clustering Reveals Robust Neurophysiological Subtypes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with substantial variability in motor and cognitive features. Conventional clinical scales provide limited insight into underlying neural mechanisms and show poor longitudinal stability.
Daniel Vered, Zoya Katzir, Idan Daniel Grosbard, Avner Thaler, Inbal Maidan   +4 more
wiley   +1 more source

Examining the Effect of Anti-seizure Medications Monotherapy on Cognitive Functions in Patients with Epilepsy: A 1-month Longitudinal Study

Archives of Epilepsy
Objective: Cognitive impairment in epilepsy is one of the most important problems affecting daily life. This study aimed to investigate the change in cognitive functions of patients with epilepsy a month after starting anti-seizure medications (ASMs ...
Hatice Eraslan Boz, Dilara Mermi Dibek, İbrahim Öztura, Barış Baklan   +3 more
doaj   +1 more source

On the Necessity of "Appropriate Behavior" on the Part of teh Caregiver [PDF]

, 1978
Bischof, Norbert
core   +1 more source

A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia

Movement Disorders, EarlyView.
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson, Isaac Adanyeguh, David J. Arpin, Tetsuo Ashizawa, Benjamin Bender, Fernando Cendes, Xi Chen, Giulia Coarelli, Léo Coutinho, Andreas Deistung, Imis Dogan, Alexandra Durr, Jennifer Faber, for the ESMI MR Study Group, Juan Fernandez‐Ruiz, Mónica Ferreira, Marcondes C. França, Sophia L. Göricke, Shuo Han, Thomas Klockgether, Chen Liu, Jun Luo, Alberto R.M. Martinez, Sergio E. Ono, Chiadi U. Onyike, Gülin Öz, for the EUROSCA MR Study Group, Henry Paulson, Jerry L. Prince, Kathrin Reetz, Thiago J.R. Rezende, Matthis Synofzik, Hélio A. Ghizoni Teive, Sophia I. Thomopoulos, Paul M. Thompson, Dagmar Timmann, David Vaillancourt, Bart van de Warrenburg, Judith van Gaalen, Xingang Wang, Philipp Wegner, Sarah H. Ying, Ian H. Harding, Carlos R. Hernandez‐Castillo   +43 more
wiley   +1 more source

Why it is time to develop the use of cognitive event-related potentials in the treatment of psychiatric diseases

Neuropsychiatric Disease and Treatment, 2013
Salvatore CampanellaLaboratory of Medical Psychology and Addictology, ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, Brussels, BelgiumAbstract: The relapse rate for many psychiatric disorders is staggeringly high, indicating that
Campanella S
doaj  

Association between sleep duration and cognitive function and emotional disorders in middle‐aged and elderly patients with cerebral small vessel disease

Sleep Research, EarlyView.
Abstract Objectives To investigate the association between the sleep duration with cognitive impairment in middle‐aged and elderly patients with cerebral small vessel disease (CSVD). Methods This cross‐sectional study enrolled hospitalized patients aged ≥55 years diagnosed with CSVD between November 2021 and August 2023.
Chunmei Long, Yunying Wu, Sha Wang, Ziwei Gong, Ye Wang   +4 more
wiley   +1 more source

Beyond device parameters: psychological predictors of spinal cord stimulation success and their neurobiological mechanisms—a narrative review

Frontiers in Psychology
Spinal cord stimulation (SCS) represents an established treatment for refractory chronic pain, yet significant outcome variability persists despite technological advances. This narrative review examines why psychological factors assume central importance
Anna B. Marcinkowska, Anna B. Marcinkowska, Anna B. Marcinkowska, Jakub Wiśniewski, Michał Sobstyl, Sara Kierońska-Siwak, Paweł J. Winklewski, Paweł J. Winklewski   +7 more
doaj   +1 more source

Longitudinal simultaneous DBS fMRI in the rodent brain [PDF]

, 2016
Boon, Paul, Dauwe, Ine, Descamps, Benedicte, Raedt, Robrecht, Van Den Berge, Nathalie, Van Holen, Roel, van Mierlo, Pieter, Vanhove, Christian, Vonck, Kristl   +8 more
core   +1 more source

Research on sleep quality and influencing factors among medical staff in a tertiary hospital in Anhui Province, China

Sleep Research, EarlyView.
To assess sleep quality and identify key influencing factors among medical staff in a tertiary hospital to support health policy development. Conducted in July 2024 using validated scales: Pittsburgh Sleep Quality Index (PSQI); Depression, Anxiety, and Stress Scale‐21; and Assessed: sleep quality, latency, disturbances, and daytime dysfunction.
Xiao‐Ying Jin, Ting Jiang, Ri‐Hong Wei, Meng‐Dan Chu, Han Li, Shan Zhang, Zeng‐Feng Su   +6 more
wiley   +1 more source