Results 1 to 10 of about 89 (80)
Abstract Background Colombia hosts the largest Autosomal‐Dominant Alzheimer's Disease (ADAD) kindred caused by the PSEN1‐E280A genetic variant, with full penetrance. This ADAD is well‐characterized in terms of clinical and biomarker research, but Electroencephalography (EEG) as a biomarker is still under development. EEG facilitates understanding brain
Juliana Moreno Rada +6 more
wiley +2 more sources
Abstract INTRODUCTION Adverse social conditions across the life course influence brain aging and dementia, yet their compounded impact on clinical phenotypes remains underexplored, particularly in Latin America, where social inequality and dementia burden are high.
Temitope Farombi +36 more
wiley +1 more source
Abstract Autosomal dominant Alzheimer's disease (ADAD) represents a small but impactful subset of Alzheimer's cases. Asymptomatic individuals at genetic risk face substantial personal and family implications when considering predictive testing for known familial variants.
Daniel A. Jiménez +26 more
wiley +1 more source
Abstract This study aimed to assess the acute cardiac autonomic responses to high and low intensity resistance training and their association with post exercise hypotension in adults with pharmacologically treated hypertension. This randomized clinical trial included 31 participants with pharmacologically treated hypertension.
Luis A. Benavides‐Roca +2 more
wiley +1 more source
Abstract In the present study, 43 Italian school‐age children (age range = 7–14 years, 16 females) with (N = 19) and without DD (N = 24) were presented with pairs of visual displays separated by varying interstimulus intervals and performed either a temporal integration or segregation task despite an identical visual input.
Giuseppe Di Dona +4 more
wiley +1 more source
Neuropsicologia da Esquizofrenia
O objetivo deste capítulo foi descrever a neurobiologia e o perfil de comprometimento cognitivo da esquizofrenia. A esquizofrenia é o tipo mais comum de psicose, caracterizada por etiologia heterogênea (fatores genéticos, bioquímicos, endócrinos, de neurodesenvolvimento e psicossociais), manifestações clínicas multiformes e variabilidade no curso da ...
Nina e Silva, Claudio Herbert +2 more
openaire +2 more sources
Abstract Background Resting‐state EEG (rsEEG) alterations in the posterior alpha rhythm are promising biomarkers of neurodegenerative diseases (NDDs). However, spectral analysis often overlooks the rsEEG non‐rhythmic (aperiodic) component. Studies assessing the oscillatory and aperiodic activity are scarce and frequently underpowered. While multicenter
Alberto Jaramillo‐Jimenez +15 more
wiley +1 more source
Abstract Background Graph metrics have been used to evaluate functional connectivity in Alzheimer's disease (AD). It has been found that nodal and global graph metrics are altered in subjects with AD and MCI compared to controls. In subjects with mutations associated with autosomal dominant Alzheimer's disease (ADAD), these metrics may vary depending ...
Claudia Aponte +6 more
wiley +1 more source
Abstract Background The periodic (e.g., EEG alpha power density) and aperiodic (offset and slope of EEG power density) components of resting‐state EEG rhythms reflect different aspects of global neural dynamics and have been linked to excitatory/inhibitory balance.
Matteo Carpi +13 more
wiley +1 more source

