Results 61 to 70 of about 380,497 (264)

Editorial: Ecological Disaster Neuropsychiatry

open access: yesFrontiers in Psychiatry, 2021
Konstantin Loganovsky   +3 more
doaj   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

open access: yesAdvanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang   +9 more
wiley   +1 more source

Distinguishing Perception from Evidence in Psychiatrists’ Attitudes Toward Second-Generation Long-Acting Injectable Antipsychotics [Letter]

open access: yesNeuropsychiatric Disease and Treatment
Yoshiyo OguchiDepartment of Neuropsychiatry, Teikyo University Mizonokuchi Hospital, Kawasaki, Kanagawa, JapanCorrespondence: Yoshiyo Oguchi, Department of Neuropsychiatry, Teikyo University Mizonokuchi Hospital, 5-1-1, Futago, Takatsu-ku, Kawasaki ...
Oguchi Y
doaj  

Case report—Depression with psychotic features as an atypical presentation of neurosyphilis

open access: yesClinical Case Reports
Key Clinical Message Recurrent depression with psychotic features is an atypical presentation of neurosyphilis. This case emphasizes the polymorphic clinical presentation of neurosyphilis and how it mimics affective disorders with psychotic symptoms.
Aykut Aytulun   +6 more
doaj   +1 more source

Where the boundary violations are going? Is there a return to neuropsychiatry?

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Boundaries of psychiatry have been changing and the field has been exposed to violation and incursion for a long time. Psychiatry has many common interests with other behavioral sciences, mainly Neurology and Psychology.
Nazan Aydın
doaj  

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

DDSurfer: A Weakly‐Supervised Dual‐Stream Deep Learning Framework for Cortical Surface Reconstruction From Diffusion MRI

open access: yesAdvanced Science, EarlyView.
DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li   +10 more
wiley   +1 more source

Mini-review: Translational Value of Rodent Models in Behavioral Neuropsychiatry

open access: yesImpulse: The Premier Undergraduate Neuroscience Journal, 2022
Model organisms have become the transformative tools for biological discovery of the cellular and molecular processes that underlie human disease pathogenesis.
John Calvo, Jr., Natalya Khutsishvili
doaj  

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong   +13 more
wiley   +1 more source

Nanotherapeutics and Psychopathology: Revolutionizing Mental Health Diagnosis and Treatment with Bioengineered Nanoplatforms [PDF]

open access: yesNanomedicine Research Journal
This review evaluates how nanotherapeutics can improve the diagnosis and treatment of psychopathology by addressing limitations of conventional pharmacotherapy, such as poor blood–brain (BBB) barrier penetration and off-target effects in disorders like ...
Abdul Amir H. Kadhum   +6 more
doaj   +1 more source

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