Results 51 to 60 of about 124,099 (309)

Early cognitive decline in amyotrophic lateral sclerosis and its relation to driving: an observational study

Journal of Rehabilitation Medicine
Objective: To determine whether early cognitive function in amyotrophic lateral sclerosis patients predicts future cognitive function and the decision to cease driving. Design: Observational study. Subjects: Patients with amyotrophic lateral sclerosis.
Tina Taule, Ole-Bjørn Tysnes, Jörg Aßmus, Annbjørg Spilde Morland, Marit Arnevik Renså, Tone Revheim, Synnøve Glesnes, Tiina Rekand   +7 more
doaj   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Altered Resting-State Functional Connectivity of Multiple Networks and Disrupted Correlation With Executive Function in Major Depressive Disorder

Frontiers in Neurology, 2020
Background: Major depressive disorder (MDD) is one of the most common and costly psychiatric disorders. In addition to significant changes in mood, MDD patients face an increased risk of developing cognitive dysfunction.
Yujie Liu, Yujie Liu, Yaoping Chen, Xinyu Liang, Danian Li, Yanting Zheng, Yanting Zheng, Hanyue Zhang, Ying Cui, Jingxian Chen, Jiarui Liu, Shijun Qiu   +11 more
doaj   +1 more source

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow, Nicola McKern, Vincent Oxenham, Kate Ahmad, Omar Ahmad   +4 more
wiley   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Neuropsychological and Educational Profile of Children with Dyscalculia and Dyslexia: A Comparative Study

Psico-USF, 2019
This paper aims to compare the neuropsychological and educational profiles of Brazilian children with dyscalculia (n = 8), dyslexia (n = 13) and without learning disabilities (n = 12).
Magda Solange Vanzo Pestun, Rauni Jandé Roama-Alves, Sylvia Maria Ciasca   +2 more
doaj   +1 more source

Guideline-conform translation and cultural adaptation of the Addenbrooke’s Cognitive Examination III into German

GMS German Medical Science, 2020
Objective: Age-related disorders, such as dementia, significantly contribute to the global burden of disease. Adequate screening in the primary care setting is critical for early detection and proper management.
Weiss, Björn, Grunow, Julius J., Rosenthal, Max, Hilfrich, David, Mörgeli, Rudolf, Neuner, Bruno, Borchers, Friedrich, Kraft, Antje, Krampe, Henning, Denke, Claudia, Spies, Claudia D.   +10 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

A 5-min Cognitive Task With Deep Learning Accurately Detects Early Alzheimer's Disease

Frontiers in Aging Neuroscience, 2020
Introduction: The goal of this study was to investigate and compare the classification performance of machine learning with behavioral data from standard neuropsychological tests, a cognitive task, or both.Methods: A neuropsychological battery and a ...
Ibrahim Almubark, Ibrahim Almubark, Lin-Ching Chang, Kyle F. Shattuck, Thanh Nguyen, Raymond Scott Turner, Xiong Jiang   +6 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source