Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms: A pilot study. [PDF]
Lawrence MR +4 more
europepmc +1 more source
Self‐completed patient‐reported outcome measures in adults with epilepsy: A review
Abstract Epilepsy affects 65 million people worldwide, and is a World Health Organization priority disease as highlighted in their 2022–2031 Intersectoral Global Action Plan (IGAP) on Epilepsy and other Neurological Disorders. IGAP's objectives include improving epilepsy treatment and care.
Alison L. Conquest +5 more
wiley +1 more source
Among common neuropsychological tests, the Paced auditory serial addition test is the strongest predictor of trait fatigue in patients with traumatic brain injury. [PDF]
Berginström N +3 more
europepmc +1 more source
Abstract Objective Late‐onset unexplained epilepsy (LoUE), defined as epilepsy onset after age 55 without an obvious cause, is an important risk factor for dementia. Studies have shown that 10%–25% of individuals with LoUE develop dementia within 3–4 years following their first seizure.
Alice D. Lam +13 more
wiley +1 more source
Eye Tracking as Biomarker Compared to Neuropsychological Tests in Parkinson Syndromes: An Exploratory Pilot Study Before and After Deep Transcranial Magnetic Stimulation. [PDF]
Cont C +4 more
europepmc +1 more source
Neuropsychological Tests for Patients with Marchiafava-Bignami Disease: A Case Report. [PDF]
Youn H, Lee SI, Kim SG, Lee J, Jung HY.
europepmc +1 more source
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha +27 more
wiley +1 more source
Predicting the Progression of Mild Cognitive Impairment to Alzheimer's Dementia Using Recurrent Neural Networks With a Series of Neuropsychological Tests. [PDF]
Park C +9 more
europepmc +1 more source

