Results 231 to 240 of about 233,627 (306)

Agreement and 2‐year trajectories of youth‐ and parent‐reported health‐related quality of life in youth with epilepsy treated with surgery vs medical therapy

open access: yesEpilepsia, EarlyView.
Abstract Objective This cohort study examined the agreement between youth‐ and parent‐reported health‐related quality of life (HRQOL) of children treated with epilepsy surgery compared to medical therapy. A second aim was to evaluate whether changes in HRQOL over 2 years differed between the two groups, and to determine whether these trajectories ...
Mary Lou Smith   +2 more
wiley   +1 more source

Performance of the 5‐SENSE score in a pediatric and young adult cohort of 100 consecutive stereoelectroencephalography cases

open access: yesEpilepsia, EarlyView.
Abstract This study assesses the validity of the 5‐SENSE score in a cohort of pediatric patients with epilepsy and evaluates associations between the score, ancillary testing, and surgical outcomes. We retrospectively calculated the 5‐SENSE score in a single‐center predominantly pediatric cohort and calculated the sensitivity and specificity for ...
Lindsey Trank   +7 more
wiley   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie   +10 more
wiley   +1 more source

Pediatric sensorimotor cortical responsiveness to intracerebral stimulation during stereoelectroencephalographic monitoring: Age effects and area specificity

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to determine how age influences clinical responsiveness to intracerebral electrical stimulation (IES) in children across primary and secondary sensorimotor cortices and to assess age effects on response complexity and area‐specific responsiveness.
Giulia Nobile   +10 more
wiley   +1 more source

Stereo‐EEG mapping of visual working memory with task‐related high‐gamma modulations

open access: yesEpilepsia, EarlyView.
Abstract Objective We describe a safe, informative, and easy‐to‐implement approach for presurgical mapping of visual working memory (VWM) with stereo‐electroencephalography (SEEG). Methods Twenty‐four patients with drug‐resistant epilepsy, 11–23 years of age, performed a single‐probe change detection VWM task, during SEEG monitoring.
Brian Ervin   +13 more
wiley   +1 more source

Stereo‐electroencephalography–guided cross‐electrode radiofrequency thermocoagulation in focal epilepsy: A review of current methodologies and outcomes

open access: yesEpilepsia, EarlyView.
Abstract Advances in stereo‐electroencephalography–guided radiofrequency thermocoagulation (SEEG‐guided RFTC) have led to the development of cross‐electrode RFTC, which has been shown to result in significantly larger lesions and higher seizure‐freedom rates compared to standard RFTC methods.
Bethany Campbell   +10 more
wiley   +1 more source

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