Results 101 to 110 of about 112,414 (193)

Intracranial stimulation for pediatric refractory epilepsy: A single institutional experience using evolving therapies

Epilepsia Open, EarlyView.
Abstract Objective Neuromodulation for pediatric refractory epilepsy (PRE) is preferred when the seizure onset zone is not amenable to surgical resection, due to multifocal onset or involvement of eloquent cortex. Given its rapidly evolving landscape, we describe our institutional experience with neurostimulation therapies including deep brain ...
Rohin Singh, Megan M. J. Bauman, Karimul Islam, Panagiotis Kerezoudis, Sanjeet S. Grewal, Jonathon J. Parker, Jamie J. Van Gompel, Kai J. Miller, Brian N. Lundstrom, Keith Starnes   +9 more
wiley   +1 more source

Phenotype and surgical management of drug‐resistant epilepsy in patients with COL4A1 and COL4A2 variants

Epilepsia Open, EarlyView.
Abstract Objective To summarize the clinical features of collagen type IV alpha 1/2 chain (COL4A)1/2‐related epilepsy and the seizure outcomes of patients undergoing epilepsy surgery. Methods We retrospectively analyzed the clinical, electroencephalography, and neuroimaging data; genetic characteristics; surgical details; and prognosis of 8 patients (4
Jie Shi, Jiuluan Lin, Jianjun Bai, Haixiang Wang, Bingqing Zhang, Qian Feng, Zhaohui Sun, Yiou Liu, Jing He, Xiancheng Song, Siyu Wang, Xiaoyan Liu, Wenjing Zhou   +12 more
wiley   +1 more source

Subjective memory complaints in people with epilepsy: Are there “signature” complaints associated with anxiety and depression?

Epilepsia Open, EarlyView.
Abstract Objective While there is a relatively weak association between cognitive complaints and performance on standardized tests of memory function, elevated levels of depression and anxiety are highly correlated with subjective memory complaints in people with epilepsy (PWE).
Cassandra Trend, Isha Puntambekar, Sallie Baxendale   +2 more
wiley   +1 more source

Impact of hippocampectomy on seizure freedom in temporal encephaloceles: A systematic review and individual participant data meta‐analysis

Epilepsia Open, EarlyView.
Abstract Objective Temporal encephaloceles (TEs) are increasingly recognized as a cause of MRI‐negative temporal lobe epilepsy (TLE). The optimal surgical approach for TE‐related refractory epilepsy remains unclear, particularly regarding the necessity of excluding mesiotemporal structures such as the hippocampus, which may lead to worse ...
Panagiota‐Eleni Tsalouchidou, Alexandros Matsingos, Wiebke Hahn, Katja Menzler, Susanne Knake   +4 more
wiley   +1 more source

Regional epilepsy: Unraveling the epileptic phenomenon

Epileptic Disorders, EarlyView.
Shreyashish Roy‐Chowdhury, Elma Paredes‐Aragon, Richard S. McLachlan, Jorge G. Burneo, David A. Steven, Ana Suller Marti   +5 more
wiley   +1 more source

The relationship between neuromagnetic networks and cognitive impairment in self‐limited epilepsy with centrotemporal spikes

Epilepsia Open, EarlyView.
Abstract Objective This was an exploratory study designed to examine the alterations in neuromagnetic networks within brain regions involved in cognitive functions in children with self‐limited epilepsy with centrotemporal spikes (SeLECTS). Additionally, it sought to explore the relationship between these neural network differences and cognitive ...
Jing Lu, Peilin Jiang, Yingfan Wang, Minghao Li, Yinjie Zhu, Ke Hu, Xinyi Zhou, Xiaoshan Wang   +7 more
wiley   +1 more source

Facilitators and barriers to neurologist referral of patients for epilepsy surgery evaluation

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy surgery offers a potential cure for drug‐resistant epilepsy (DRE), yet surgery is underutilized. An estimated 5% of patients with DRE undergo long‐term EEG monitoring (LTM) annually, the requisite first step of evaluation for surgical candidacy.
Chloé E. Hill, Daniel Hochster, Jessica E. Baker, Alison L. Herman, Nishad Shaheid, Susanna S. O'Kula, Jack M. Parent, Darin B. Zahuranec, Lesli E. Skolarus   +8 more
wiley   +1 more source

The landscape of epilepsy surgery in older adults: Challenges and opportunities

Epilepsia Open, EarlyView.
Abstract The prevalence of epilepsy increases with age, and with the aging population, the number of drug‐resistant epilepsy (DRE) cases is expected to rise. However, epilepsy surgery remains underutilized and is typically offered to younger adults. Despite historical hesitancy due to concerns over risks and outcomes, evidence over the last two decades
Vineet Punia
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Oxytocin Amplifies Negative Response to Ambiguity in Adolescent Females With and Without Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Eating disorders (ED) typically emerge in adolescence, a critical period for brain development and peer bonding. Interpersonal difficulties—particularly social anxiety—frequently co‐occur with ED. Oxytocin is a neuropeptide that modulates social cognition and linked to prosocial effects.
Victoria Burmester, Emerie Sheridan, Nikita Catalina Julius, Jordan Elliott, Olivia Thackeray, Dasha Nicholls   +5 more
wiley   +1 more source