Results 51 to 60 of about 65,465 (230)

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Psychological predictors of negative treatment outcome with Erenumab in chronic migraine: data from an open label long-term prospective study

The Journal of Headache and Pain, 2021
Background Monoclonal antibodies (mABs) targeting the calcitonin gene-related peptide (CGRP) pathway represent the first disease-specific preventive migraine therapy.
Bottiroli Sara, Roberto De Icco, Gloria Vaghi, Stefania Pazzi, Elena Guaschino, Marta Allena, Natascia Ghiotto, Daniele Martinelli, Cristina Tassorelli, Grazia Sances   +9 more
doaj   +1 more source

The Timecourse of Electrophysiological Brain–Heart Interaction in DoC Patients

Brain Sciences, 2021
Disorders of Consciousness (DOC) are a spectrum of pathologies affecting one’s ability to interact with the external world. Two possible conditions of patients with DOC are Unresponsive Wakefulness Syndrome/Vegetative State (UWS/VS) and Minimally ...
Francesco Riganello, Martina Vatrano, Simone Carozzo, Miriam Russo, Lucia Francesca Lucca, Maria Ursino, Valentina Ruggiero, Antonio Cerasa, Camillo Porcaro   +8 more
doaj   +1 more source

Simultaneous bilaternal training for improving arm function after stroke [PDF]

, 2009
Background Simultaneous bilateral training, the completion of identical activities with both arms simultaneously, is one intervention to improve arm function and reduce impairment.
Coupar, Fiona, Langhorne, Peter, Morris, Jacqui, Pollock, Alex, Van Wijck, Frederike   +4 more
core   +3 more sources

Wavy‐Interlocked Stretchable Triboelectric Nanogenerators Enhanced by Liquid Metal Microflowers for Self‐Powered Wearable Motion Monitoring

Advanced Science, EarlyView.
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu, Huimin Li, Hanmin Zeng, Yahui Meng, Yimeng He, Xinke Hu, Senfeng Zhao, Jianxun Zhang, Peiqiong Zhou, Kechao Zhou, Dou Zhang, Chris Bowen, Yan Zhang   +12 more
wiley   +1 more source

Neurorehabilitation technologies and functional recovery after brain injury: influence of sex, an integrative review

Frontiers in Digital Health
BackgroundAcquired brain injury (ABI), which includes traumatic brain injury (TBI) and stroke, is a leading cause of disability. Evidence shows that sex may influence functional recovery post-acquired brain injury, potentially due to biological (e.g ...
Phoebe Bennett, Phoebe Bennett, Neil Barr   +2 more
doaj   +1 more source

Riemannian Geometry for the Classification of Brain States with Intracortical Brain Recordings

Advanced Intelligent Systems, EarlyView.
Geometric machine learning is applied to decode brain states from invasive intracortical neural recordings, extending Riemannian methods to the invasive regime where data is scarcer and less stationary. A Minimum Distance to Mean classifier on covariance manifolds uses geodesic distances to outperform convolutional neural networks while reducing ...
Arnau Marin‐Llobet, Sergio Sánchez‐Manso, Arnau Manasanch, Lluc Tresserras, Xinhe Zhang, Yining Hua, Hao Zhao, Melody Torao‐Angosto, Maria V Sanchez‐Vives, Leonardo Dalla Porta   +9 more
wiley   +1 more source

Electronic Archive on the Topics “Neurorehabilitation”, “Neurorehabilitation in Rare Diseases” and “Robotic Neurorehabilitation”

Digital Presentation and Preservation of Cultural and Scientific Heritage
The frequency of neurological diseases and neurosurgical conditions is increasing in last decades, especially in Eastern Europe. This fact imposes the necessity of amelioration of the quality of care, and, subsequently – of the quality of education of ...
Radoslav R. Yoshinov, Borislav Yoshinov, Ivet Koleva   +2 more
doaj   +1 more source

Tiempo es cerebro ¿solo en la fase aguda del ictus? [PDF]

, 2012
Introduction and objective: In Spain, stroke is the leading cause of death in women as well as the leading cause of disability in adults. This translates into a huge human and economic cost.
Carmona-Abellan, M. (M.), Meyer, M. (M.), Murie, M. (M.), Ortega-Cubero, S. (Sara), Teasell, R. (R.)   +4 more
core   +1 more source

Infantile‐Onset Ascending Hereditary Spastic Paraplegia due to a Homozygous ALS2 Exons 24–25 Deletion: Expanding the Genotypic Spectrum

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona, Maria Gnazzo, Silvia Genovese, Gessica Vasco, Lorena Travaglini, Maurizio Sabbadini, Marina Macchiaiolo, Francesco Nicita, Jacopo Sartorelli, Carmelo Piscopo, Enrico Castelli, Enrico Bertini, Andrea Bartuli, Antonio Novelli, Gessica Della Bella, Davide Vecchio   +15 more
wiley   +1 more source