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Neuroscience and Law ::Complicated Crossings and New Perspectives /
There have been extraordinary developments in the field of neuroscience in recent years, sparking a number of discussions within the legal field. This book studies the various interactions between neuroscience and the world of law, and explores how ...
Errigo, Maria Chiara., D'Aloia, Antonio.
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Evolutionary Theory in Cognitive Neuroscience: A 20-Year Quantitative Review of Publication Trends
Evolutionary cognitive neuroscience is an emerging and promising new scientific field that combines the meta-theoretical strengths of an evolutionary perspective with the methodological rigor of neuroscience.
Gregory D. Webster
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Neuroscience research in Africa: Current status
There are limited data on the contribution of the African continent to neuroscience research and publications. This review aims to provide a clear view on the state of neuroscience research among African countries, and to compare neuroscience research ...
Foad Abd-Allah +7 more
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Miami Neuroscience Institute - Winter 2021
https://scholarlycommons.baptisthealth.net/bg-bh-neuroscience-news/1004/thumbnail ...
Miami Neuroscience Institute
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Summary: Haploinsufficiency of the SHANK3 gene is causally linked to autism spectrum disorders (ASDs) in human genetic studies. Here we found that chemogenetic activation of pyramidal neurons in the prefrontal cortex (PFC) of Shank3-deficient mice with ...
Luye Qin, Kaijie Ma, Zhen Yan
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
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Systematic Identification of Cell-Cell Communication Networks in the Developing Brain
Summary: Since the generation of cell-type specific knockout models, the importance of inter-cellular communication between neural, vascular, and microglial cells during neural development has been increasingly appreciated.
Bilal N. Sheikh +10 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
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Theoretical Models of Neural Development
Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues.
Geoffrey J. Goodhill
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