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Neurobiology and neuroscience discoveries

ABSTRACT:In the past decade, advancements in neurobiology and neuroscience have substantially enhanced our understanding of the brain's intricate mechanisms and the neural underpinnings of behavior and cognition. Cutting-edge technologies such as optogenetics, CRISPR-Cas9 gene editing, and advanced imaging techniques have facilitated groundbreaking ...
Chandra Panda, Krishna   +2 more
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Neuroscience: Setting the neurobiological occasions for hierarchical learning and inference

Current Biology
Hierarchical associations help animals navigate the environment by using contextual and latent states to guide learning and behavior. Chemogenetic inactivation in an occasion setting task reveals that orbitofrontal cortex is essential for implementing a hierarchical task structure, yet both orbitofrontal cortex and dorsal hippocampus are required for ...
Maryam, Ratemi, Matthew P H, Gardner
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A Systems Approach to Behavioral Neurobiology: Integrating Psychodynamics and Neuroscience in a Psychiatric Curriculum

Psychodynamic Psychiatry, 2006
In the practice of medicine, an understanding of the biological functioning of organs and organ systems is the basis for theories of pathology and clinical practice. If psychoanalysis is to be accepted by the medical and psychiatric community, it must be based on a sophisticated understanding of the organ from which mental and emotional experiences ...
Timothy J, Lacy, John D, Hughes
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Medical Neurobiology: Neuroanatomical and Neurophysiological Principles Basic to Clinical Neuroscience

JAMA: The Journal of the American Medical Association, 1973
Advances in all aspects of neuroscience have influenced and will continue to influence the practice of medicine. The number of neurologists will probably remain small relative to the frequency and seriousness with which the nervous system is affected by disease.
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The neonate-6-hydroxydopamine-lesioned rat: a model for clinical neuroscience and neurobiological principles

Brain Research Reviews, 2005
In 1973, a technique of administering 6-hydroxydopamine (2,4,5-trihydroxyphenylethylamine) intracisternally to neonate rats was introduced to selectively reduce brain dopamine (neonate-lesioned rat). This neonate treatment proved unique when compared to rats lesioned as adults with 6-hydroxydopamine--prompting the discovery of differing functional ...
George R, Breese   +5 more
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[The neurobiology of sleep: Cajal and present-day neuroscience].

Revista de neurologia, 2004
We briefly describe the most significant findings obtained recently concerning the sleep-waking cycle in comparison to the studies conducted by Cajal on the same subject.This paper includes a short biographical sketch of Santiago Ramón y Cajal, with special emphasis on his importance within the framework of neuroscience.
J L, Velayos-Jorge   +2 more
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Translational Clinical Neuroscience Perspectives on the Cognitive and Neurobiological Mechanisms Underlying Alcohol-Related Aggression

2013
Alcohol-related violence, a longstanding, serious, and pervasive social problem, has provided researchers from diverse disciplines with a model to study individual differences in aggressive and violent behavior. Of course, not all alcohol consumers will become aggressive after drinking and similarly, not all individuals with alcohol use disorders will ...
Anne, Beck   +2 more
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Intersections of Neurobiology and Oncology: Foundations and Frontiers in Cancer Neuroscience

Cancer neuroscience encompasses a multidisciplinary field that investigates the intricate interactions between the nervous system and cancer biology, particularly within the context of tumorigenesis, metastasis, and therapeutic responses. This burgeoning area of research explores the bidirectional communication between cancer cells and neural tissues ...
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Neuroscience of alcohol for addiction medicine: Neurobiological targets for prevention and intervention in adolescents.

Progress in brain research, 2017
Structural and functional neuroimaging studies indicate that heavy alcohol use during adolescence may be neurotoxic to the brain. This chapter reviews the neuroimaging findings in cross-sectional and longitudinal studies of adolescent heavy alcohol users.
Anita, Cservenka, Bonnie J, Nagel
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Neurobiological Aspects of Ethanol-Derived Salsolinol in NEUROSCIENCE OF ALCOHOL: Mechanisms and Treatment

2019
SUMMARY POINTS 1. Ethanol acts through glutamate and GABA, but indirectly necessitates dopamine, opioid peptides, adenosine, and serotonin neurotransmission. 2. Ethanol acts through the involvement of ethanol- derived acetaldehyde. 3. Acetaldehyde is a highly reactive, electrophilic molecule. 4.
Acquas Elio   +2 more
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