Results 11 to 20 of about 5,279 (107)

Enhancing Dopamine Accumulation in Secretory Vesicles of PC12 Cells: Mechanisms, Applications and Limitations. [PDF]

J Neurochem
Schematic representation of a large dense‐core vesicle in PC12 cells highlighting its main molecular organization. The diagram illustrates the presence of membrane transporters, proton pumps and intravesicular matrix proteins that establish the electrochemical gradients required for neurotransmitter uptake, vesicle acidification and efficient storage ...
Socas-Pérez N, Borges R, Machado JD.
europepmc   +2 more sources

Type III CD38 is present in the membrane of neurosecretory vesicles and has a cytosol-facing catalytic domain in primate oxytocin neurons. [PDF]

J Neuroendocrinol
Abstract CD38, an ADP‐ribosyl cyclase that generates cyclic ADP‐ribose (cADPR), is essential for Ca2+‐dependent oxytocin release. However, its subcellular localisation and membrane topology within oxytocin neurones have remained unclear. We investigated the distribution and orientation of CD38 in oxytocin‐producing neurones of Japanese macaques (Macaca
Miyamoto T, Matsushima A, Otubo A, Song C, Murata K, Oti T, Sakamoto H.   +6 more
europepmc   +2 more sources

Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells. [PDF]

Chembiochem
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Beauvais B, Rohokale R, Mamputu S, Lupu I, Guo Z, Balieu S.   +5 more
europepmc   +2 more sources

Electrophysiological recording of hypothalamic brain regions in vivo using the transpharyngeal surgical approach in the rat. [PDF]

J Neuroendocrinol
Abstract Transpharyngeal (ventral) surgery in urethane‐anaesthetised rats allows in vivo electrophysiological recording and/or imaging from superficial hypothalamic brain regions and from the pituitary gland. This surgical approach leaves the whole brain intact, providing a stable platform to study single or multiple identified cells over several hours
Ludwig M, Leng G, Brown CH.
europepmc   +2 more sources

Research Progress on the Effect of Exercise and Neurobiological Mechanism on Depression [PDF]

Zhongguo quanke yixue, 2022
Exercise has been confirmed by most studies to be effective in preventing and treating depression, and has become a recommended treatment by many researchers.
Shaokun WANG, Shiqiang WANG, Yijie WANG, Zhihan XU
doaj   +1 more source

Pheochromocytoma-paraganglioma type 5 syndrome associated with mutation in the succinate dehydrogenase type A complex (SDHA), a case report

Iatreia, 2023
Pheochromocytomas and paragangliomas are rare neuroendocrine neoplasms that can produce catecholamines, with an incidence of less than one case per million inhabitants.
Myriam Vanessa Rueda-Galvis, Alejandro Román-Gonzaléz, Valentina Agredo-Delgado   +2 more
doaj   +1 more source

A Hypothesis Regarding Neurosecretory Inhibition of Stress Mediators by Colchicine in Preventing Stress-Induced Familial Mediterranean Fever Attacks

Frontiers in Immunology, 2022
Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disease characterized by recurrent episodes of fever and serositis. Colchicine (Col) has a crucial role in the prevention of amyloidosis and FMF attacks.
Cengiz Korkmaz, Döndü Üsküdar Cansu, Güven Barıs Cansu   +2 more
doaj   +1 more source

Unveiling the sensory and interneuronal pathways of the neuroendocrine connectome in Drosophila

eLife, 2021
Neuroendocrine systems in animals maintain organismal homeostasis and regulate stress response. Although a great deal of work has been done on the neuropeptides and hormones that are released and act on target organs in the periphery, the synaptic inputs
Sebastian Hückesfeld, Philipp Schlegel, Anton Miroschnikow, Andreas Schoofs, Ingo Zinke, André N Haubrich, Casey M Schneider-Mizell, James W Truman, Richard D Fetter, Albert Cardona, Michael J Pankratz   +10 more
doaj   +1 more source

Neuroendocrine gastric carcinoma in a young patient [PDF]

Vojnosanitetski Pregled, 2010
Background. Neuroendocrine tumors cover a spectrum of neoplasms showing wide variations in their clinicopathological and pathogenetic features, as well as prognosis. They may develop throughout the whole gastrointestinal tract. Case report.
Svorcan Petar, Alimpijević Tamara, Ušaj Slavica, Bojić Danijela, Protić Marjana, Đorđević Jelena, Vrinić Dušica, Krstić Miodrag, Dapčević Branka   +8 more
doaj   +1 more source

Neuroendocrine differentiation as a survival prognostic factor in advanced non-small cell lung cancer [PDF]

Vojnosanitetski Pregled, 2007
Beckground/Aim. Neuroendrocine lung tumors are histologically heterogenous group of cancers with different clinical progression. In non-small cell lung cancer (NSCLC) neuroendocrine differentiation exists in 10-30% of patients.
Petrović Marina, Tomić Ilija, Ilić Srbislav   +2 more
doaj   +1 more source