Results 41 to 50 of about 22,677,162 (222)

Dual cholinergic and serotonergic excitatory pathways mediate oxygen sensing in the zebrafish gill

The Journal of Physiology, Volume 603, Issue 22, Page 7123-7144, November 15, 2025.
Abstract figure legend The present study identified two sub‐populations of gill oxygen sensing neuroepithelial cells (NECs) distinguishable by their stored neurotransmitters – serotonin (5‐hydroxytryptamine, 5‐HT) or acetylcholine (ACh). Using transgenic Tg(elavl3:GCaMP6s) zebrafish, which express an endogenous calcium reporter in neurons, we ...
Maddison Reed, Anthea A. Mavridis, Jan A. Mennigen, Michael G. Jonz   +3 more
wiley   +1 more source

Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan, Rongjiao Xi, Yong Kang, Ming‐jie Kuang, Xiaoyuan Ji   +4 more
wiley   +1 more source

Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract BACKGROUND The apolipoprotein E (APOE) gene includes the strongest protective (ε2) and risk (ε4) variants for sporadic Alzheimer's disease (AD), but underlying mechanisms remain unclear. We studied APOE genotype effects on the cerebrospinal fluid (CSF) proteome.
Eleonora M. Vromen, Senne B. Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Lars Bertram, Johannes Streffer, Simon Lovestone, Stephanie J. B. Vos, Mikel Tainta, Yvonne Freund‐Levi, Lutz Frölich, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Frans Verhey, Rik Vandenberghe, Jolien Schaeverbeke, Kaj Blennow, Sven J. van der Lee, Philip Scheltens, Yolande A. L. Pijnenburg, Wiesje M. van der Flier, Charlotte E. Teunissen, Henrik Zetterberg, Pieter Jelle Visser, Betty Tijms   +26 more
wiley   +1 more source

Revealing the Impact of Mono(2‐ethylhexyl) Phthalate (MEHP) on Prostate Cancer Based on Network Toxicology and Molecular Docking Approaches

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2078-2094, October 2025.
ABSTRACT Mono(2‐ethylhexyl) phthalate (MEHP) is a ubiquitous environmental contaminant and endocrine‐disrupting chemical (EDC), identified as a potential carcinogen. Emerging studies have begun to elucidate the impact of MEHP on prostate cancer (PCa), yet its pathogenic effects and the underlying molecular mechanisms remain unclear. This study seeks to
Chenyu Liang, Weicheng Tian, Hengxi Zeng, Ziyang Xia, Zijie Luo, Yue Zhuo, Minlian Pan, Kangbu Wu, Siyu Xiong, Xuejing Lin, Xinchun Li, Jiaxi Yu   +11 more
wiley   +1 more source

Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila

Cellular and Molecular Life Sciences, 2017
Multiple neuropeptides are known to regulate water and ion balance in Drosophila melanogaster. Several of these peptides also have other functions in physiology and behavior.
Meet Zandawala, Richard Marley, S. Davies, D. Nässel   +3 more
semanticscholar   +1 more source

Glucagon-like and insulin-like hormones of the insect neurosecretory system [PDF]

, 1976
Howard S. Tager, J. Markese, Karl J. Kramer, Roy D. Speirs, Cynthia N. Childs   +4 more
openalex   +1 more source

The functional role of hypothalamo- hypophysial neurosecretory system in fish migrations and spawning

, 2020
П.Е. Гарлов
openalex   +1 more source

Potential for Polysialylated Form of Neural Cell AdhesionMolecule-Mediated Neuroplasticity within the Gonadotropin-ReleasingHormone Neurosecretory System of the Ewe* [PDF]

, 2001
Catherine Viguié, Heiko T. Jansen, J. David Glass, Michiko Watanabe, Heather J. Billings, Lique M. Coolen, Michael N. Lehman, Fred J. Karsch   +7 more
openalex   +1 more source

Hypothalamic-pituitary neurosecretory system in myocardial infarction

Kazan medical journal, 1982
In 22 patients who died from myocardial infarction, the paraventricular and supraoptic nuclei of the hypothalamus and neurohypophysis were morphologically examined (Gomori-Gabi staining). The sizes of neurons and their nuclei were increased. Vacuolated cells were observed at a high concentration of nagum in the blood.
openaire   +1 more source

Neurosecretory system of the earwig Labedura riparia, and the rôle of the aorta as a neurohaemal organ

, 1975
V.B. Awasthi
openalex   +1 more source