Results 181 to 190 of about 35,266 (337)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine is a potent regulator of neurotransmission and neuronal excitability, through activation of Gi coupled adenosine A1 receptors (A1Rs). Adenosine has gained interest as an anticonvulsant because of its endogenous involvement in ending seizure activity, but peripheral side effects require local application.
Erine Craey, Marijke Vergaelen, Serge Van Calenbergh, Jeroen Spanoghe, Evelien Carrette, Kristl Vonck, Paul Boon, Wytse J. Wadman, Robrecht Raedt   +8 more
wiley   +1 more source

Temporary Transvenous Diaphragm Neurostimulation Preserves PaO2/FiO2 Ratio Over 50 Hours of Mechanical Ventilation [PDF]

, 2021
Elizabeth Rohrs, Thiago Bassi, K. Fernández, Jessica Wittmann, Marlena Ornowska, Michelle Nicholas, Steven Reynolds   +6 more
openalex   +1 more source

Normalization of deviance in neuromodulation for epilepsy

Epilepsia, EarlyView.
Abstract The rapid expansion of neuromodulation therapies for drug resistant epilepsy has introduced a growing risk of normalization of deviance (NoD). This occurs when incremental deviations from established procedures are iteratively reinterpreted as the care standard in the absence of immediate adverse outcomes.
Karim Mithani, George M. Ibrahim
wiley   +1 more source

Neurostimulation [PDF]

Zeitschrift für Epileptologie, 2014
openaire   +1 more source

Neuropsychological outcomes comparing traditional surgical approaches and laser interstitial thermal therapy for refractory mesial temporal lobe epilepsy: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract Objective This systematic review and meta‐analysis aimed to compare neuropsychological outcomes following traditional surgical approaches and magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) in patients with drug‐resistant mesial temporal lobe epilepsy.
Konstantina Stavrogianni, Katerina Poprelka, Theodoros Fasilis, Vasileios Giannopapas, Wiebke Hahn, Iris Gorny, Aristotelis Kalyvas, Lampis Stavrinou, Sotirios Giannopoulos, Efstathios Boviatsis, Georgios Tsivgoulis, Anastasios Bonakis, Susanne Knake, Panagiota‐Eleni Tsalouchidou   +13 more
wiley   +1 more source

The looping lullaby: closed-loop neurostimulation decreases sleepers’ sensitivity to environmental noise [PDF]

, 2021
Vidushi Pathak, Elsa Juan, Reina van der Goot, Lucia M. Talamini   +3 more
openalex   +1 more source

Lennox–Gastaut syndrome unveiled: Advancing diagnosis, therapies, and advocacy‐insights from the Genoa International Workshop

Epilepsia, EarlyView.
Abstract Lennox–Gastaut syndrome (LGS) is one of the most severe, yet one of the most discussed, childhood‐onset developmental and epileptic encephalopathies (DEEs). Dissent among epileptologists on the definition and minimum set of electroclinical features derives from the high etiological heterogeneity within the syndrome, which could make its ...
Antonella Riva, Gianluca D'Onofrio, Elisabetta Amadori, Alexis Arzimanoglou, Stéphane Auvin, Irene Bagnasco, Paola Barabino, Valentina Biagioli, Isabella Brambilla, Giuliana Cangemi, Antonietta Coppola, Antonella De Lillo, Carlo Di Bonaventura, Giancarlo Di Gennaro, Edoardo Ferlazzo, Antonio Gil‐Nagel, Giuseppe Gobbi, Simona Lattanzi, Gerhard Kluger, Günter Krämer, Maria Margherita Mancardi, Carlo Minetti, Lino Nobili, Elisa Paravati, Milka Pringsheim, Erika Rebessi, Antonino Romeo, Angelo Russo, Emilio Russo, Katia Santoro, Susanne Schubert‐Bast, Laura Siri, Jo Sourbron, Maria Stella Vari, Alberto Verrotti, Flavio Villani, Maurizio Viri, Celina von Stülpnagel, Nelia Zamponi, Federico Zara, Pasquale Striano   +40 more
wiley   +1 more source

Diaphragm Neurostimulation Assisted Ventilation in Critically Ill Patients.

American Journal of Respiratory and Critical Care Medicine, 2023
Harry Etienne, Idunn S Morris, G. Hermans, L. Heunks, E. Goligher, S. Jaber, C. Morélot-Panzini, J. Assouad, J. Gonzalez-Bermejo, L. Papazian, T. Similowski, A. Demoule, M. Dres   +12 more
semanticscholar   +1 more source

Utility of stereo‐electroencephalography in patients with bilateral independent/unclear scalp electroencephalographic seizure onset

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to determine whether bilateral independent or unclear (BI/U) scalp electroencephalographic (EEG) ictal onset patterns may predict the diagnostic yield of stereo‐electroencephalography (SEEG) and inform surgical decision‐making in patients with focal drug‐resistant epilepsy.
Aayesha J. Soni, M. Claudia Burbano, R. Grace Couper, Poul H. Espino, John A. L. Perez, Amit Persad, Khalid Alorabi, Poornima N. Nambiar, Arun Thurairajah, David Diosy, Michelle‐Lee Jones, Ana Suller Marti, Keith W. MacDougall, Jonathan C. Lau, David A. Steven, Jorge G. Burneo, Giovanni Pellegrino   +16 more
wiley   +1 more source