Results 71 to 80 of about 18,537 (259)

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano, Carolina Gorodetsky, Darcia Paul, Jürgen Germann, Aaron Loh, Han Yan, Peter L. Carlen, Sara Breitbart, Andres M. Lozano, George M. Ibrahim, Suneil K. Kalia   +10 more
wiley   +1 more source

Extended coverage of human serum glycosphingolipidome by 4D-RP-LC TIMS-PASEF unravels association with Parkinson’s disease

Nature Communications
Glycosphingolipids (GSLs) are important targets in immune, infectious, lysosomal storage diseases, cancer, and neurodegenerative diseases. Circulatory GSLs profiling in clinical samples is restricted by the lack of mid- and high-throughput analytical ...
Huong Giang Vo, Gabriel Gonzalez-Escamilla, Daniela Mirzac, Lilia Rotaru, Damian Herz, Sergiu Groppa, Laura Bindila   +6 more
doaj   +1 more source

Neurostimulation for treatment of post-stroke impairments [PDF]

Neurostimulation, the use of electrical stimulation to modulate the activity of the nervous system, is now commonly used for the treatment of chronic pain, movement disorders and epilepsy.
Dawson, Jesse, Abdul-Rahim, Azmil H., Kimberley, Teresa J.   +2 more
core   +1 more source

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

Epilepsia, EarlyView.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger, Xinbing Zhang, Thomas Lisko, Hafsa Farooqi, Steffen Ventz, Sandipan Pati, Thomas R. Henry, David P. Darrow, Michael C. Park, Theoden I. Netoff, Robert A. McGovern   +10 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Neurostimulation approaches to primary headache disorders

, 2009
Purpose of review: Conventional management options in medically intractable chronic-headache syndromes, such as chronic migraine, chronic cluster headache and hemicrania continua, are often limited. This review summarizes the current concepts, approaches
Bartsch, Thornston, Goadsby, Peter, Paemeleire, Koen   +2 more
core   +1 more source

Stereo‐electroencephalography–guided responsive neuromodulation: A propensity‐matched cohort study

Epilepsia, EarlyView.
Abstract Objective The optimal pre‐implantation evaluation and surgical targeting strategies for responsive neurostimulation (RNS) in patients with unresectable, drug‐resistant focal epilepsy continue to be debated. Although stereo‐electroencephalography (sEEG) is central to characterizing the seizure‐onset zone, its role in preoperative testing for ...
David Botros, Julian Brown, John D. Rolston, Paul A. House, Amir Arain, Matthew Jensen, Blake Newman, Brian Johnson, Sindhu Richards, Angela Peters, Shervin Rahimpour, Ben Shofty   +11 more
wiley   +1 more source

Sphenopalatine ganglion: block, radiofrequency ablation and neurostimulation - a systematic review

The Journal of Headache and Pain, 2017
Background Sphenopalatine ganglion is the largest collection of neurons in the calvarium outside of the brain. Over the past century, it has been a target for interventional treatment of head and facial pain due to its ease of access.
Kwo Wei David Ho, Rene Przkora, Sanjeev Kumar   +2 more
doaj   +1 more source

Effect of time to palliative epilepsy surgery on outcomes

Epilepsia, EarlyView.
Abstract Objective Epilepsy duration is a modifiable risk factor in the outcome of definitive epilepsy surgery; however, an analogous effect in palliative procedures has not been shown. We reviewed the Pediatric Epilepsy Surgery Database data for an association between epilepsy duration and seizure reduction in palliative procedures.
Robert M. Crutcher, David E. Horvat, Avery R. Caraway, Kristen H. Arredondo, Taylor J. Abel, Nitin Agarwal, Allyson L. Alexander, Dallas Michael Armstrong, Kurtis I. Auguste, Danilo Bernardo, Jeffrey Bolton, David Bonda, Dewi Frances Depositario‐Cabacar, Krista Eschbach, William D. Gaillard, Aran Groves, Jason S. Hauptman, Pradeep K. Javarayee, Cemal Karakas, Andrew T. Knox, Jenny J. Lin, Patricia E. McGoldrick, Derryl J. Miller, Edward John Novotny, Adam P. Ostendorf, Pilar D. Pichon, Shilpa B. Reddy, Debopam Samanta, Rani K. Singh, Janelle L. Wagner, Steven M. Wolf, Lily C. Wong‐Kisiel, Fernando N. Galan, M. Scott Perry, Michael A. Ciliberto   +34 more
wiley   +1 more source

Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective

Oral Oncology Reports
Xerostomia, or dry mouth, is a condition characterised by a decrease in salivary flow rate, affecting the quality of life of many individuals. Factors contributing to xerostomia include radiation therapy, pathologies, medications, and age-related loss of
Rajkumar Krishnan, Nagarathinam Anbu Elangovan, Ramya Ramadoss   +2 more
doaj   +1 more source