Results 111 to 120 of about 479,147 (344)

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

Advanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao, Yi Wu, Haiyang Wang, Chenchun Zhang, Ying Zhu, Yan Jiang, Changyou Jiang, Qiumin Le, Xing Liu, Lan Ma, Feifei Wang   +10 more
wiley   +1 more source

A Practice of General Anaesthesia for Neurosurgery [PDF]

, 1960
ROBERT I. W. BALLANTINE
openalex   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

The impact of the COVID-19 pandemic on neurosurgery in the elderly population in Sweden

BMC Public Health
Background The COVID-19 pandemic prompted a refocus of health care resources to acute care which has impacted on the capacity of healthcare systems to conduct neurological surgeries.
Michael Axenhus, Sophia Schedin-Weiss, Lars Tjernberg, Bengt Winblad   +3 more
doaj   +1 more source

Deep learning in neurosurgery: a systematic literature review with a structured analysis of applications across subspecialties

Frontiers in Neurology
ObjectiveThis study systematically reviewed deep learning (DL) applications in neurosurgical practice to provide a comprehensive understanding of DL in neurosurgery.
Kivanc Yangi, Jinpyo Hong, Arianna S. Gholami, Thomas J. On, Alexander G. Reed, Pravarakhya Puppalla, Jiuxu Chen, Jiuxu Chen, Carlos E. Calderon Valero, Yuan Xu, Baoxin Li, Marco Santello, Michael T. Lawton, Mark C. Preul   +13 more
doaj   +1 more source

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

Advanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang, Jiangang Zhang, Yiran Li, Zihan Zhong, Wenhua Li, Haojun Luo, Yanyong Liu, Liujian Ouyang, Zhuoran Jiang, Yuning Sun, Hang Sun, Lulu Liu, Huayu Yang, Yu Wang, Nan Yang, Wenbin Ma, Yilei Mao   +16 more
wiley   +1 more source

SOME EFFECTS OF INADVERTENT HYPOTHERMIA IN INFANT NEUROSURGERY [PDF]

, 1960
PAUL R. HACKETT, R. M. N. Crosby
openalex   +1 more source

Neurosurgery [PDF]

New England Journal of Medicine, 1939
openaire   +3 more sources

Delirium in neurosurgery [PDF]

Acta Neurochirurgica, 2019
Martin N. Stienen, Martin N. Stienen
openaire   +4 more sources