Results 281 to 290 of about 493,832 (328)

Prospective inter‐individual analysis of quality‐adjusted life years (QALYs) in brain tumor patients: A comprehensive assessment of health preferences

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Eloquent intracranial tumors present unique challenges in neurosurgical treatment due to their proximity to critical functional areas of the brain. This prospective, single‐center cohort study quantified real‐time changes in patients' subjective burden of health impairments using the Time Trade‐Off and Standard Gamble methods, providing ...
Lisa S. Hönikl   +4 more
wiley   +1 more source

Development and validation of clinical screening systems for Cushing disease in the United States. [PDF]

open access: yesPituitary
Salcedo-Sifuentes JE   +26 more
europepmc   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

open access: yesInternational Journal of Cancer, EarlyView.
What's New? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak   +31 more
wiley   +1 more source

iMeta Conference 2025: Creating high‐impact international journals

open access: yesiMeta, EarlyView.
The iMeta Conference 2025, part of the iMeta Conference series, themed “Creating High‐Impact International Journals,” held at the Huangjiahu Campus of Hubei University of Chinese Medicine from August 23rd to 25th, 2025, and focused on frontier topics such as microbiology, medicine, traditional Chinese medicine, botany, and research career development ...
Zhihao Zhu   +229 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Single‐cell RNA sequencing reveals the niche transitions in the non‐small cell lung cancer microenvironment mediated by piR‐hsa‐164586 during the invasive and metastatic processes

open access: yesInterdisciplinary Medicine, EarlyView.
A novel mechanism of metastasis of non‐small cell lung cancer (NSCLC) involving piR‐hsa‐164586 was elucidated by single‐cell RNA sequencing. piR‐hsa‐164586 accelerates the invasion and metastasis of NSCLC by activating the PI3K‐AKT pathway and epithelial‐mesenchymal transition.
Yan Tang   +16 more
wiley   +1 more source

Spine endoscopic surgery establishment for disc disease (Neurocore-SENSED): an open and decentralized consensus. [PDF]

open access: yesBrain Spine
Al Barajraji M   +17 more
europepmc   +1 more source

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