Results 331 to 340 of about 326,305 (400)

Comprehensive Review of Early and Late Toxicities in CAR T-Cell Therapy and Bispecific Antibody Treatments for Hematologic Malignancies. [PDF]

Cancers (Basel)
Bangolo A, Amoozgar B, Mansour C, Zhang L, Gill S, Ip A, Cho C.   +6 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies. [PDF]

J Immunother Cancer
Fleischer A, Kurth S, Duell J, Topp M, Strunz PP, Mersi J, Rasche L, Sanges C, Hudecek M, Einsele H, Maatouk I.   +10 more
europepmc   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Addressing graft-versus-host disease in allogeneic cell-based immunotherapy for cancer. [PDF]

Exp Hematol Oncol
Lyu Z, Niu S, Fang Y, Chen Y, Li YR, Yang L.   +5 more
europepmc   +1 more source

Four-hour versus 24-hour intravenous infusion of FK 506 in liver transplantation [PDF]

, 1991
Abu-Elmagd, KM, Alessiani, M, Draviam, R, Fung, J, Jain, A, Shannon, W, Starzl, TE, Takaya, S, Todo, S, Tzakis, A, Venkataramanan, R, Warty, VS   +11 more
core  

Organ‐on‐Chip: The Future of Nutrition Research in a One Health World

Food Frontiers, EarlyView.
Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta, Maria Elexpuru‐Zabaleta, Sandra Sumalla Cano, Yasmany Armas Diaz, Francesca Giampieri, Zou Xiaobo, Di Zhang, Giuseppe Grosso, Maurizio Battino   +8 more
wiley   +1 more source

Delivery of Natural Small Molecules Through Nanocarriers for Cancer Treatment

Food Frontiers, EarlyView.
Natural small molecules through nanocarriers for cancer treatment ABSTRACT Cancer is a formidable adversary, accounting for the second highest number of fatalities worldwide. A multitude of studies have indicated that naturally sourced small‐molecule compounds, owing to their low toxicity and multi‐target capabilities, significantly aid in the fight ...
Fangting Ye, Shaojie Zheng, Shuo Shan, Jiaer Cai, Yufan Liu, Weichao Chen, Xinxin He, Chao Zhao   +7 more
wiley   +1 more source

Rare but relevant: Nitrous oxide and peripheral neurotoxicity, what do we know? [PDF]

Addiction
Brunt TM, van den Brink W, van Amsterdam J.   +2 more
europepmc   +1 more source

Olive Leaf Extracts With High, Medium, or Low Bioactive Compounds Content Differentially Modulate Alzheimer's Disease via Redox Biology

Food Frontiers, EarlyView.
Olive leaf (OL) extracts were assessed for biomedical and phytochemical profiles. High‐OL extract was the most effective in inhibiting AChE, COX‐2, and iron‐reducing activity. Low‐ and high‐OL extracts showed significant effects against Aβ and tau toxicity in vivo. All extracts modulated redox biology at different levels. Only high‐OL extract prevented
Jose M. Romero‐Marquez, María D. Navarro‐Hortal, Alfonso Varela‐López, Rubén Calderón‐Iglesias, Juan G. Puentes, Francesca Giampieri, Maurizio Battino, Cristina Sánchez‐González, Jianbo Xiao, Roberto García‐Ruiz, Sebastián Sánchez, Tamara Y. Forbes‐Hernández, José L. Quiles   +12 more
wiley   +1 more source