Results 341 to 350 of about 472,869 (430)

Major depressive disorder on a neuromorphic continuum. [PDF]

Nat Commun
Li J, Long Z, Ji GJ, Han S, Chen Y, Yao G, Xu Y, Zhang K, Zhang Y, Cheng J, Wang K, Chen H, Liao W.   +12 more
europepmc   +1 more source

Chemical Characterization, Antioxidant, and Anticholinesterase Activities of Libidibia ferrea (Mart. Ex Tul.) L.P.Queiroz and In Silico Studies with the Acetylcholinesterase Enzyme

Chemistry &Biodiversity, EarlyView.
ABSTRACT Libidibia ferrea is used in many parts of Brazil for a variety of conditions, such as inflammation, respiratory disorders, muscle pain, and gastrointestinal problems. This study evaluated the chemistry and antioxidant and acetylcholinesterase (AChE) inhibitory activities of L. ferrea extracts. Hydroethanolic extracts of leaves (ELLF) and bark (
Lucas Soares Frota, Sara Ingrid Caetano Gomes Barbosa, Camila Costa Feitosa, Francisco Flávio da Silva Lopes, Daniel Pereira de Oliveira, Leonardo Soares Freitas, Adriano Lincoln Albuquerque Mattos, Wildson Max Barbosa da Silva, Hamilton Mitsugu Ishiki, Selene Maia de Morais   +9 more
wiley   +1 more source

Neurotransmitter Systems Affected by PBDE Exposure: Insights from In Vivo and In Vitro Neurotoxicity Studies. [PDF]

Toxics
García-Suastegui WA, Navarro-Mabarak C, Silva-Adaya D, Dolores-Raymundo HG, Alvarez-Gonzalez MY, León-Olea M, Ramos-Chávez LA.   +6 more
europepmc   +1 more source

Graphene Derivatives as Efficient Transducing Materials for Covalent Immobilization of Biocomponents in Electrochemical Biosensors

ChemElectroChem, EarlyView.
This review explores the transformative role of graphene derivatives in electrochemical biosensors for diagnostics, environmental monitoring, and industrial sensing. Highlighting innovations in synthesis and covalent functionalization, it discusses how these materials enhance biosensor stability, specificity, and scalability.
Petr Jakubec, David Panáček, Martin‐Alex Nalepa, Marianna Rossetti, Ruslan Álvarez‐Diduk, Arben Merkoçi, Majlinda Vasjari, Lueda Kulla, Michal Otyepka   +8 more
wiley   +1 more source

Causal relationship between gut microbiota, blood metabolites and autism spectrum disorder: a Mendelian randomization study. [PDF]

R Soc Open Sci
Wang J, Dou HH, Liang QY.
europepmc   +1 more source

Laser‐Induced Graphene for Early Disease Detection: A Review

ChemElectroChem, Volume 12, Issue 6, March 15, 2025.
Laser‐induced graphene (LIG) has emerged as a superior alternative to conventionally synthesized graphene due to its flexibility, cost‐effectiveness, scalability, high conductivity, and the ability to customize its properties for various applications. This review highlights LIG′s transformative potential in electrochemical biosensing, focusing on early
Sri Ramulu Torati, Gymama Slaughter
wiley   +1 more source

Clinical features, plasma neurotransmitter levels and plasma neurohormone levels among patients with early-stage Parkinson's disease with sleep disorders. [PDF]

Cell Commun Signal
Ma CH, Ren N, Xu J, Chen L.
europepmc   +1 more source

Further Structure‐Activity Relationship of G Protein‐Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds

ChemMedChem, EarlyView.
Work presented here details the design and characterize novel G protein‐gated inwardly rectifying potassium channels (GIRK)1/2 activators. A new 4,4‐difluorocyclohexylpyrazole have been identified that confers improved potency and selectivity for GIRK1/2 versus GIRK1/4.
Sumaiya Nahid, Fahad Imtiaz Rahman, Yu Du, Brittany D. Spitznagel, Sandeep K. Singh, Yashpal S. Chhonker, Daryl J. Murry, C. David Weaver, Corey R. Hopkins   +8 more
wiley   +1 more source

Efficacy and exploratory analysis of potential mechanisms of stellate ganglion block in alleviating sleep disturbance in generalized anxiety disorder: a randomized controlled trial excluding comorbid depression. [PDF]

Front Neurol
Liu N, Ma Q, Zhou M, Yang L, Wang W, Wang Y.   +5 more
europepmc   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source