Results 351 to 360 of about 472,869 (430)

Advancing FIRES Treatment: The Potential of Intrathecal Dexamethasone

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a rare, devastating epilepsy syndrome characterized by refractory status epilepticus following a febrile illness. Patient Description We describe a 12‐year‐old girl with FIRES who exhibited a remarkable clinical and electrographic response to intrathecal dexamethasone (IT‐DEX ...
Carol Park, Douglas R. Nordli III, Mohamed Taha, Henry David, Shawn Kacker, Tareq Kass‐Hout, Sonam Thind, Aurelie Hanin, Sana Said, Hiba A. Haider, Douglas R. Nordli Jr.   +10 more
wiley   +1 more source

Elucidation of the antipyretic and anti-inflammatory effect of 8-<i>O</i>-Acetyl Shanzhiside methyl ester based on intestinal flora and metabolomics analysis. [PDF]

Front Pharmacol
Li X, Liu T, Liang K, Wang R, Yang J, Chen Y, Wang R, Li M.   +7 more
europepmc   +1 more source

Brain SPECT when structural imaging fails to offer diagnostic clues [PDF]

, 2012
Peremans, Kathelijne
core  

A 2‐Part, Open‐Label, Phase 1 Bioequivalence and Food‐Effect Study of Ubrogepant in Healthy Adult Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1 study of ubrogepant was conducted to establish the bioequivalence (BE) of the 50‐ and 100‐mg to‐be‐marketed (TBM) tablet formulations with the clinical trial (CT) 100‐mg tablet formulation and evaluate the food effect on the bioavailability of the 100‐mg TBM tablet. This 2‐part study enrolled healthy participants aged 18‐45 years.
Ramesh Boinpally, Joel M. Trugman
wiley   +1 more source

A new mode of action for unconventional NMDA receptors. [PDF]

Elife
Smith I.
europepmc   +1 more source

How Amino Acids Intercalate in CaFe Layered Double Hydroxides: A Combined RIXS and NEXAFS Study

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
Intercalation of amino acids in layered double hydroxides offers a road to functional (bio)catalysts. With resonant soft x‐ray spectroscopy we probe the electronic structure of these systems and observe activation and passivation of electronic states as well as bond formation between the amino acid and the LDH upon intercalation.
R. Büchner, A. Born, K. Ruotsalainen, R. Decker, A. Pietzsch   +4 more
wiley   +1 more source

Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration. [PDF]

Mol Neurodegener
Shen T, Vogel JW, Van Deerlin VM, Suh E, Dratch L, Phillips JS, Massimo L, Lee EB, Irwin DJ, McMillan CT.   +9 more
europepmc   +1 more source

Prenatal and Early Childhood Exposure to Antibiotics or Gastric Acid Inhibitors and Increased Risk of Epilepsy: A Nationwide Population‐Based Study

Clinical Pharmacology &Therapeutics, EarlyView.
Over 10 million children in the world have epilepsy, with an unknown cause in half of the cases. The gut microbiome has been associated with various neurological disorders, and certain drugs greatly disturb the microbiome. Our aim was to study the association of prenatal and childhood exposure (before the age of two) to antibiotics, proton pump ...
Unnur Gudnadottir, Ronny Wickström, Anna Gunnerbeck, Stefanie Prast‐Nielsen, Nele Brusselaers   +4 more
wiley   +1 more source

Cerebrospinal fluid profiles of targeted metabolomics on neurotransmitters in patients with post-neurosurgical bacterial meningitis. [PDF]

Front Cell Infect Microbiol
Mei Z, Guan L, Xu Z, Cheng H, Ye L.
europepmc   +1 more source

Utilization of Medicinal Plants in Mental Disorders: Neuroplasticity and Neuroprotection in Biomodels. [PDF]

Brain Sci
Estela-Zape JL, Sanclemente-Cardoza V, Noreña-Buitrón LD, Ordoñez-Mora LT.   +3 more
europepmc   +1 more source