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Neurotrophic factors and Parkinson's disease
2007Publisher Summary Neurotrophic factors are endogenous proteins that modulate cell-signaling pathways regulating stem cell proliferation, neuronal differentiation, differentiation, growth, and regeneration. They are generally small, soluble proteins with molecular weights between 13 and 24 kDa and often function as homodimers.
Yan Chen, Greg A. Gerhardt, Don M. Gash
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The changing scene of neurotrophic factors
Trends in Neurosciences, 1991The purification of brain-derived neurotrophic factor (BDNF), the elucidation of its primary structure, and the subsequent identification of neurotrophin-3 (NT-3) ended the monopoly of NGF as the only well-characterized, target-derived neurotrophic molecule. NGF, BDNF and NT-3 are members of a gene family called neurotrophins.
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Neurotrophic Factors and Neurodegeneration
1995Neurotrophic factors (NTFs) are molecules which act to promote the differentiation of neurons and to maintain their phenotype. The discovery by Hamburger and Levi- Montalcini in 1949 that the number of neurons in dorsal root ganglia was related to the size of the target field suggested that there exists a mechanism of neuronal support by which factors ...
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The Effects of Physical Exercise and Cognitive Training on Memory and Neurotrophic Factors
Journal of Cognitive Neuroscience, 2017J. Heisz +6 more
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Neurotrophic factors (BDNF and GDNF) and the serotonergic system of the brain
Biochemistry (Moscow), 2017N. K. Popova, T. Ilchibaeva, V. Naumenko
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Role of Neurotrophic Factors in Parkinson's Disease.
Current pharmaceutical design, 2017Diogo Tomé +3 more
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Hippocampal neurogenesis, neurotrophic factors and depression: possible therapeutic targets?
CNS and Neurological Disorders - Drug Targets, 2015G. Serafini +6 more
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Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy.
Human Gene Therapy, 2015A. Domanskyi, M. Saarma, M. Airavaara
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