Viability of Tumor Cells in Bone Dust: Implications for Oncologic Skull Base Surgery
ABSTRACT Background Head and neck tumors with skull base involvement may require drilling of tumor infiltrated bone. We hypothesize that bone dust generated during this process contains viable tumor cells that may seed the surgical field. Methods Tumors with gross bone invasion were drilled, and dust was collected for H&E, cell viability analysis, and ...
Kelly Bridgham +14 more
wiley +1 more source
Bilateral nervus intermedius neuralgia with neurovascular contact: a case report highlighting hypertension and eczema as potential precipitating factors. [PDF]
Jiao S, Zhou Y, Zhu Y, Zhang Z, Ma H.
europepmc +1 more source
The Neuromuscular System Is Part of Brain Health
Brain Health, EarlyView.
Wolfgang Grisold
wiley +1 more source
ABSTRACT Introduction A Phase II trial demonstrated that neoadjuvant cemiplimab was associated with pathologic complete response (pCR) in 51% of patients with locoregionally advanced cutaneous squamous cell carcinoma (cuSCC). We evaluated real‐world radiographic and pathologic responses to neoadjuvant cemiplimab and assessed radiologic–pathologic ...
Whitney Jin +14 more
wiley +1 more source
Treatment Outcomes in Osteosarcoma of the Head and Neck: A Systematic Review and Meta‐Analysis
ABSTRACT Background Head and neck osteosarcomas (HNOS) are rare, accounting for ~1% of head and neck malignancies. This study systematically evaluated the role of chemotherapy (CT) and radiotherapy (RT) on survival outcomes. Methods A systematic review and meta‐analysis were performed following PRISMA guidelines across six databases.
Angela Magri +12 more
wiley +1 more source
ABSTRACT Background H&N Merkel cell carcinoma (MCC) mainly affects elderly patients, yet age‐stratified treatment patterns and outcomes data are scarce. Methods We analyzed 88 consecutive H&N MCC patients (2000–2022) by age (< 75 vs. ≥ 75 years). OS was estimated by Kaplan–Meier analysis and MCC‐specific death with competing‐risks methods (cause ...
Igor Vainer +3 more
wiley +1 more source
Immune-endothelial crosstalk at the nexus of neuroinflammation and vascular dysfunction in aging. [PDF]
Cui Z, Sun H, Chen Z, Li J.
europepmc +1 more source
Reconstructing Skull Base Reconstruction: The State of the Art
ABSTRACT Background Skull base reconstruction has continued to evolve in parallel with advances in endoscopic skull base ablation in order to accomplish the goal of restoring larger and more complicated defects between the cranial and nasal cavities while balancing morbidity, cost, and recovery.
Muhammad El Shatanofy +2 more
wiley +1 more source
Short-, Mid-, and Long-Term Outcomes Following Open Displaced Bicondylar Tibial Plateau Fractures in a Large Retrospective Cohort. [PDF]
Jawich B +11 more
europepmc +1 more source
Finding My Path: Listening, Learning, and Leading in Rare Disease: The 2025 Hower Award
Annals of the Child Neurology Society, EarlyView.
Andrea Gropman
wiley +1 more source

