Results 51 to 60 of about 2,856,138 (288)

Oscillations in Higher-Order Neutral Differential Equations

open access: yesCanadian Journal of Mathematics, 1993
AbstractConsider the n-th order (n ≥ 1 ) neutral differential equation where σ1 < σ 2 < ∞ and μ and η are increasing real-valued functions on [Ƭ1, Ƭ2] and [σ1, σ2] respectively. The function μ is assumed to be not constant on [Ƭ1, Ƭ2] and [Ƭ1, Ƭ2] for every Ƭ ∈ (Ƭ1, Ƭ2) similarly, for each σ ∈ (σ1, σ2), it is supposed that r\ is not constant on
Philos, C. G.   +2 more
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

New Aspects for Non-Existence of Kneser Solutions of Neutral Differential Equations with Odd-Order

open access: yes, 2020
Some new oscillatory and asymptotic properties of solutions of neutral differential equations with odd-order are established. Through the new results, we give sufficient conditions for the oscillation of all solutions of the studied equations, and this ...
Dumitru Baleanu, Ali Muhib, Osama Moaaz
core   +1 more source

Periodic Solution for a Kind of Third-Order Neutral-Type Differential Equation

open access: yesJournal of Function Spaces, 2023
In this paper, we investigate a class of a third-order neutral-type differential equation with time-varying delays. Some sufficient conditions on the existence of a periodic solution are established for the considered system.
Axiu Shu, Bo Du
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Averaging Method for Neutral Stochastic Delay Differential Equations Driven by Fractional Brownian Motion

open access: yesJournal of Function Spaces, 2020
In this paper, we investigate the stochastic averaging method for neutral stochastic delay differential equations driven by fractional Brownian motion with Hurst parameter H∈1/2,1.
Peiguang Wang, Yan Xu
doaj   +1 more source

Oscillation of Second Order Nonlinear Neutral Differential Equations

open access: yesMathematics, 2022
The study of the oscillatory behavior of solutions to second order nonlinear differential equations is motivated by their numerous applications in the natural sciences and engineering.
Yingzhu Wu, Yuanhong Yu, Jinsen Xiao
doaj   +1 more source

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