Results 21 to 30 of about 327,860 (265)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Some Oscillatory Criteria for Second-Order Emden–Fowler Neutral Delay Differential Equations

Mathematics
In this paper, by using the Riccati transformation and integral inequality technique, we establish several oscillation criteria for second-order Emden–Fowler neutral delay differential equations under the canonical case and non-canonical case ...
Haifeng Tian, Rongrong Guo
doaj   +1 more source

Oscillation Analysis Algorithm for Nonlinear Second-Order Neutral Differential Equations

Mathematics, 2023
Differential equations are useful mathematical tools for solving complex problems. Differential equations include ordinary and partial differential equations.
Liang Song, Shaodong Chen, Guoxin Wang
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Neutral delay equations from and for population dynamics

Electronic Journal of Qualitative Theory of Differential Equations, 2008
For a certain class of neutral differential equations it is shown that these equations can serve as population models in the sense that they can be interpreted as special cases or caricatures of the standard Gurtin-MacCamy model for a population ...
K. P. Hadeler
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Equivalence Transformation for Neutral Differential Equations: Oscillation of Solutions

Mathematics
We introduce an equivalence transformation to study the oscillation behavior of solutions for linear neutral differential equations of canonical and noncanonical types. The new approach leads to several novel oscillation criteria.
Ağacık Zafer, Tuncay Candan, Zeynep Nilhan Gürkan   +2 more
doaj   +1 more source

Oscillation Criteria in Higher Order Neutral Equations

Journal of Mathematical Analysis and Applications, 1994
The paper deals with oscillatory criteria for the solutions of a scalar higher order neutral equation of mixed type (with delayed and advanced arguments), with constant coefficients. As a main result, the classical characterization of oscillations by the characteristic equation is extended to such equations.
Bilchev, S. J., Grammatikopoulos, M. K., Stavroulakis, I. P.   +2 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Periodic solution for ϕ-Laplacian neutral differential equation

Open Mathematics, 2019
This paper is devoted to the existence of a periodic solution for ϕ-Laplacian neutral differential equation as follows (ϕ(x(t)−cx(t−τ))′)′=f(t,x(t),x′(t)).$$\begin{array}{} (\phi(x(t)-cx(t-\tau))')'=f(t,x(t),x'(t)). \end{array}$$
Yao Shaowen, Cheng Zhibo
doaj   +1 more source