Results 21 to 30 of about 169 (168)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The Neutral Stochastic Integrodifferential Equations with Jumps [PDF]
Chinese Journal of Mathematics, 2016 We study the existence and uniqueness of mild solutions for neutral stochastic integrodifferential equations with Poisson jumps under global and local Carathéodory conditions on the coefficients by means of the successive approximation. Furthermore, we give the continuous dependence of solutions on the initial value.
openaire +2 more sources
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Attractivity for neutral functional differential equations
Discrete and Continuous Dynamical Systems - B, 2013 We study the long term dynamics of non-autonomous functional di fferential equations. Namely, we establish existence results on pullback attractors for non-linear neutral functional di erential equations with time varying delays. The two main results di er in smoothness properties of delay functions.
Caraballo Garrido, Tomás, Kiss, Gábor
openaire +3 more sources
On a Quasi‐Neutral Approximation to the Incompressible Euler Equations [PDF]
Journal of Applied Mathematics, 2012 We rigorously justify a singular Euler‐Poisson approximation of the incompressible Euler equations in the quasi‐neutral regime for plasma physics. Using the modulated energy estimates, the rate convergence of Euler‐Poisson systems to the incompressible Euler equations is obtained.
Jianwei Yang, Zhitao Zhuang
openaire +3 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
On the oscillation of certain mixed neutral equations
Applied Mathematics Letters, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tuncay Candan, Rajbir S. Dahiya
openaire +2 more sources