Results 71 to 80 of about 2,608,305 (328)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Regarding at the Circular Plates Rigidity with Radial Ribs, Neglecting the Welding Seams Influence. Ribs with Constant Thickness and Lineal Variable Heighness on Length, Placed Just on a Face

Scientific Bulletin of Valahia University: Materials and Mechanics, 2022
On base of obtained results in working [1], in a certain case one should take account the lineal chamfering of ribs upon the neutral fiber position and of the circular and plane plate bending rigiditybwith radial ribs. The illustration of the theoretical
Popa Carmen, Anghelina Violeta Florina, Despa Veronica   +2 more
doaj   +1 more source

[3-Methoxy-5-(methoxycarbonyl)isoxazol-4-yl](4-methoxyphenyl)iodonium 2,2,2-trifluoroacetate

IUCrData, 2023
A new isoxazole-based iodonoium salt, C13H13INO5+·C2F3O2−, has been synthesized and structurally characterized. In the crystal, ions are linked by short I...O contacts to form a neutral tetra-ion aggregate.
Mohd Abdul Fatah Abdul Manan, David B. Cordes, Alexandra M. Z. Slawin, David O'Hagan   +3 more
doaj   +1 more source

Constraints on Gamma-ray Emission from the Galactic Plane at 300 TeV [PDF]

, 1997
We describe a new search for diffuse ultrahigh energy gamma-ray emission associated with molecular clouds in the galactic disk. The Chicago Air Shower Array (CASA), operating in coincidence with the Michigan muon array (MIA), has recorded over 2.2 x 10 ...
A. Borione, Aharonian F. A., Aharonian F. A., B. E. Fick, B. J. Newport, Bloemen J. B. G. M., C. E. Covault, Covault C. E., D. B. Kieda, D. Nitz, D. Sinclair, Dermer C. D., Drury L., Gaisser T. K., J. C. van der Velde, J. Fowler, J. Matthews, J. W. Cronin, K. D. Green, Kakimoto F., L. F. Fortson, M. A. Catanese, M. A. K. Glasmacher, M. C. Chantell, R. A. Ong, S. Oser   +25 more
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Iron Emission Lines on the Galactic Ridge Observed with Suzaku

, 2008
In order to elucidate origin of the Galactic Ridge X-ray Emission, we analyzed Suzaku data taken at various regions along the Galactic plane and studied their Fe-K emission line features.
Ebisawa, Ken, Ezoe, Yuichiro, Koyama, Katsuji, Matsumoto, Hironori, Takahashi, Hiromitsu, Tanaka, Yasuo, Yamasaki, Noriko Y., Yamauchi, Shigeo   +7 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

VENM: An Algorithm to Accurately Calculate Neutral Slopes and Gradients

Journal of Advances in Modeling Earth Systems, 2019
Mesoscale eddies stir along the neutral plane, and the resulting neutral diffusion is a fundamental aspect of subgrid‐scale tracer transport in ocean models.
Sjoerd Groeskamp, Paul M. Barker, Trevor J. McDougall, Ryan P. Abernathey, Stephen M. Griffies   +4 more
doaj   +1 more source

High-pT pi^zero Production with Respect to the Reaction Plane in Au + Au Collisions at sqrt(s_NN) = 200 GeV

, 2009
Measurements of the azimuthal anisotropy of high-\pT neutral pion neutral pion production in Au+Au collisions at sqrt(s_NN) = 200 GeV by the PHENIX experiment are presented.
Afanasiev, S., Aidala, C., Ajitanand, N. N., Akiba, Y., Al-Jamel, A., Alexander, J., Aoki, K., Aphecetche, L., Armendariz, R., Aronson, S. H., Averbeck, R., Awes, T. C., Azmoun, B., Babintsev, V., Baldisseri, A., Barish, K. N., Barnes, P. D., Bassalleck, B., Bathe, S., Batsouli, S., Baublis, V., Bauer, F., Bazilevsky, A., Belikov, S., Bennett, R., Berdnikov, Y., Bjorndal, M. T., Boissevain, J. G., Borel, H., Boyle, K., Brooks, M. L., Brown, D. S., Bucher, D., Buesching, H., Bumazhnov, V., Bunce, G., Burward-Hoy, J. M., Butsyk, S., Campbell, S., Chai, J. -S, Chernichenko, S., Chi, C. Y., Chiba, J., Chiu, M., Choi, I. J., Chujo, T., Cianciolo, V., Cleven, C. R., Cobigo, Y., Cole, B. A., Comets, M. P., Constantin, P., Csanad, M., Csorgo, T., d'Enterria, D., Dahms, T., Das, K., David, G., de Cassagnac, R. Granier, Delagrange, H., Denisov, A., Deshpande, A., Desmond, E. J., Dietzsch, O., Dion, A., Drachenberg, J. L., Drapier, O., Drees, A., Dubey, A. K., Durum, A., Dzhordzhadze, V., Efremenko, Y. V., Egdemir, J., En'yo, H., Enokizono, A., Espagnon, B., Esumi, S., Fields, D. E., Fleuret, F., Fokin, S. L., Forestier, B., Fraenkel, Z., Frantz, J. E., Franz, A., Frawley, A. D., Fukao, Y., Fung, S. -Y, Gadrat, S., Gastineau, F., Germain, M., Glenn, A., Gonin, M., Gosset, J., Goto, Y., Grau, N., Greene, S. V., Gunji, T., Gustafsson, H. A., Hachiya, T., Haggerty, J. S., Hagiwara, M. N., Hamagaki, H., Harada, H., Hartouni, E. P., Haruna, K., Harvey, M., Haslum, E., Hasuko, K., Hayano, R., He, X., Heffner, M., Hemmick, T. K., Henni, A. Hadj, Heuser, J. M., Hiejima, H., Hill, J. C., Hobbs, R., Holmes, M., Holzmann, W., Homma, K., Hong, B., Horaguchi, T., Hur, M. G., Ichihara, T., Imai, K., Inaba, M., Isenhower, D., Isenhower, L., Ishihara, M., Isobe, T., Issah, M., Isupov, A., Jacak, B. V., Jia, J., Jin, J., Jinnouchi, O., Johnson, B. M., Joo, K. S., Jouan, D., Kajihara, F., Kametani, S., Kamihara, N., Kaneta, M., Kang, J. H., Kawagishi, T., Kazantsev, A. V., Kelly, S., Khanzadeev, A., Kim, D. J., Kim, E., Kim, Y. -S, Kinney, E., Kiss, A., Kistenev, E., Kiyomichi, A., Klein-Boesing, C., Kochenda, L., Kochetkov, V., Komkov, B., Konno, M., Kotchetkov, D., Kozlov, A., Kroon, P. J., Kunde, G. J., Kurihara, N., Kurita, K., Kweon, M. J., Kwon, Y., Kyle, G. S., Lacey, R., Lajoie, J. G., Le Bornec, Y., Lebedev, A., Leckey, S., Lee, D. M., Lee, M. K., Leitch, M. J., Leite, M. A. L., Li, X. H., Lim, H., Litvinenko, A., Liu, M. X., Maguire, C. F., Makdisi, Y. I., Malakhov, A., Malik, M. D., Manko, V. I., Masui, H., Matathias, F., McCain, M. C., McGaughey, P. L., Miake, Y., Miller, T. E., Milov, A., Mioduszewski, Saskia, Mishra, G. C., Mitchell, J. T., Morrison, D. P., Moss, J. M., Moukhanova, T. V., Mukhopadhyay, D., Murata, J., Nagamiya, S., Nagata, Y., Nagle, J. L., Naglis, M., Nakamura, T., Newby, J., Nguyen, M., Norman, B. E., Nyanin, A. S., Nystrand, J., O'Brien, E., Ogilvie, C. A., Ohnishi, H., Ojha, I. D., Okada, H., Okada, K., Omiwade, O. O., Oskarsson, A., Otterlund, I., Ozawa, K., Pal, D., Palounek, A. P. T., Pantuev, V., Papavassiliou, V., Park, J., Park, W. J., Pate, S. F., Pei, H., Peng, J. -C, Perdekamp, M. Grosse, Pereira, H., Peresedov, V., Peressounko, D. Yu, PHENIX Collaboration., Pinkenburg, C., Pisani, R. P., Purschke, M. L., Purwar, A. K., Qu, H., Rak, J., Ravinovich, I., Read, K. F., Reuter, M., Reygers, K., Riabov, V., Riabov, Y., Roche, G., Romana, A., Rosati, M., Rosendahl, S. S. E., Rosnet, P., Rukoyatkin, P., Rykov, V. L., Ryu, S. S., Sahlmueller, B., Saito, N., Sakaguchi, T., Sakai, S., Samsonov, V., Sato, H. D., Sato, S., Sawada, S., Semenov, V., Seto, R., Sharma, D., Shea, T. K., Shein, I., Shibata, T. -A, Shigaki, K., Shimomura, M., Shohjoh, T., Shoji, K., Sickles, A., Silva, C. L., Silvermyr, D., Sim, K. S., Singh, C. P., Singh, V., Skutnik, S., Smith, W. C., Soldatov, A., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Staley, F., Stankus, P. W., Stenlund, E., Stepanov, M., Ster, A., Stoll, S. P., Sugitate, T., Suire, C., Sullivan, J. P., Sziklai, J., Tabaru, T., Takagi, S., Takagui, E. M., Taketani, A., Tanaka, K. H., Tanaka, Y., Tanida, K., Tannenbaum, M. J., Taranenko, A., Tarjan, P., Thomas, T. L., Togawa, M., Tojo, J., Torii, H., Towell, R. S., Tram, V. -N, Tserruya, I., Tsuchimoto, Y., Tuli, S. K., Tydesjo, H., Tyurin, N., Vale, C., Valle, H., van Hecke, H. W., Velkovska, J., Vertesi, R., Vinogradov, A. A., Vznuzdaev, E., Wagner, M., Wang, X. R., Watanabe, Y., Wessels, J., White, S. N., Willis, N., Winter, D., Woody, C. L., Wysocki, M., Xie, W., Yanovich, A., Yokkaichi, S., Young, G. R., Younus, I., Yushmanov, I. E., Zajc, W. A., Zaudtke, O., Zhang, C., Zimanyi, J., Zolin, L.   +344 more
core   +3 more sources