Results 31 to 40 of about 14,380,928 (242)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Design of neutral-point voltage controller of a three-level NPC inverter with small DC-link capacitors

, 2013
A neutral-point-clamped three-level inverter with small dc-link capacitors is presented in this paper. The inverter requires zero average neutral-point current for stable neutral–point voltage.
Munk-Nielsen, Stig, Busquets Monge, Sergio, Maheshwari, RamKrishan   +2 more
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

A neutral-point potential balance control strategy for three-level inverter based on VSVPWM

Journal of Measurement Science and Instrumentation, 2018
The topology of diode neutral-point-clamped（NPC）three-level inverter is prone to neutral-point potential offset.When the sum of three-phase current is zero,the virtual space vector pulse width modulation（VSVPWM）scheme does not cause the neutral-point ...
CHENG Dong-liang, WANG Xiao-peng, ZHU Tian-liang, MA Wen-gang   +3 more
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Active Thermal Control in Neutral-Point-Clamped Multilevel Converters based on Switching-Cell Arrays

, 2023
Neutral-Point-Clamped multilevel converters are nowadays a suitable solution to implement low-medium voltage and power applications, thanks to their intrinsic superior voltage and current quality.
Sergio Busquets-Monge (9223913), Mariana Raya (15211382), Alber Filba-Martinez (9443234), Salvador Alepuz (15211270), Roya Rafiezadeh (9272101), Joan Nicolas-Apruzzese (8154390)   +5 more
core   +1 more source

Cooperative DC-Link Voltage Regulation and Neutral-Point Balancing for an Energy-Storage-Based SOP with a Three-Level Buck–Boost Interface

Energies
With the increasing penetration of distributed generation, electric vehicles and single-phase loads in the low-voltage distribution network, flexible interconnected systems face more prominent three-phase unbalance and direct-current (DC)-side voltage ...
Yangxin Qiu, Min Yang, Jinghang Li, Xuntao Shi, Zhendong Wu, Xiaomeng He, Xin Wang   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The Role of Causal Processes in the Neutral and Nearly Neutral Theories [PDF]

, 2007
In this paper, we will consider how the neutral and nearly neutral theories of molecular evolution differ from each other as a means for addressing causal processes associated with random drift and natural selection.
Michael R. Dietrich, Millstein, Roberta L, Dietrich, Michael R, Millstein, Roberta L., Dietrich, Michael R., Dietrich, Michael, Roberta L. Millstein   +6 more
core   +1 more source