Results 61 to 70 of about 376,177 (258)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Neutral wind effects on ion outflow at Mars [PDF]
Earth, Planets and Space, 2012 This paper evaluates the influence of neutral winds on ions using the CAPIT (Combined Atmospheric Photochemistry and Ion Tracking) code, which includes ionospheric photochemistry and plasma wave energization. Based on two different wind profiles, ion outflow is, to first order, not sensitive to neutral winds.
Andersson, L., Ergun, R. E.
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2005 Observations of strong solar wind proton flux correlations with ROSAT X-ray rates along with high spectral resolution Chandra observations of X-rays from the dark Moon show that soft X-ray emission mirrors the behavior of the solar wind.
Collier +15 more
core +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Geomagnetic Disturbances Due To Neutral‐Wind‐Driven Ionospheric Currents
Space WeatherPrevious simulation efforts on geomagnetic disturbances (GMDs) and geomagnetically induced currents (GICs) mostly rely on global magnetohydrodynamics models, which explicitly calculate the magnetospheric currents and carry certain assumptions about the ...
Cheng Sheng +3 more
doaj +1 more source
Atmosphere, 2019 This study presents a new method for determining a neutral wind velocity vector. The basis of the method is measurement of the group velocities of internal gravity waves.
Andrey V. Medvedev +4 more
doaj +1 more source
Meridional thermospheric neutral wind at high latitude over a full solar cycle [PDF]
Annales Geophysicae, 1998 EISCAT radar experiments over a full solar cycle between January 1984 and March 1995 have been used to construct meridional neutral wind patterns in the ionospheric F region. For locally geomagnetically quiet periods the neutral winds have been binned
O. Witasse +4 more
doaj +1 more source
Solar cycle evolution of the solar wind in three dimensions [PDF]
, 1983 Measurements of the solar wind speed both in and out of the ecliptic are presented for 1971-82. The speed estimates, which were made with the interplanetary scintillation system at UC San Diego, have been compared to in situ for large, slowly evolving ...
Coles, W. A., Rickett, B. J.
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source