Results 121 to 130 of about 266,471 (305)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Evaluation of hot dry rock reservoir stimulation based on microseismic monitoring method: a case study of the Northern Jiangsu Basin

Frontiers in Earth Science
The reservoir stimulation is an indispensable part in the development of hot dry rock, and the evaluation of reservoir stimulation is particularly crucial for guiding the subsequent implementation of Enhanced Geothermal Systems (EGS). This paper proposes
Wenhao Xu, Xinglong Xie, Shanxin Yi, Shanxin Yi, Xianpeng Jin, Junpeng Guan, Junpeng Guan, Jun Chen, Jun Chen, Yongbiao Yang, Yongbiao Yang   +10 more
doaj   +1 more source

Photo‐Switchable Molecular Module Programming PET Biodegradation in Aquatic Environments

Advanced Functional Materials, EarlyView.
We address the plastic durability paradox by integrating an itaconic acid–derived pyrrolidone module into polymer backbones. Sunlight in water triggers Norrish Type I ring‐opening and hydrophilization, enabling rapid biodegradation into nontoxic minerals.
Mohammad Asif Ali, Jixin Zheng, Satoshi Wakai, Jie Liu, Hidetaka Nomaki, Misato Tsukatani, Noriyuki Isobe, Jingcheng Sang, Yuriko Aoki, Hideo Okamura, Daisuke Sasaki, Chiaki Ogino, Yuzo Yamazaki, Takashi Nishikaze, Kenji Takada, Maiko K. Okajima, Tatsuo Kaneko   +16 more
wiley   +1 more source

RSV and MPV neutralization assays.

, 2016
Data for each of 5 mice immunized with one of the three antigens (pre-fusion MPV F, post-fusion MPV F and RMP-1) is shown as the serum dilution required to obtain 60% neutralization.
Xiaolin Wen (2806171), Robert A. Lamb (278997), James E. Crowe Jr. (113691), George P. Leser (312089), Jarrod J. Mousa (2806174), Jennifer Pickens (2806168), Theodore S. Jardetzky (252519)   +6 more
core   +1 more source

Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation

Advanced Functional Materials, EarlyView.
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko, Djanira Rodrigues Negrão, Tanmay Gupta, Robert Jeng, Otavio Augusto Titton Dias, Maia Jaffer‐Diaz, Dinesh Christendat, Mohini Sain   +7 more
wiley   +1 more source

Temporal Variation in Bacterial Community Characteristics Shaped by Habitat in a Reservoir Buffer Strip in China

Ecology and Evolution
Habitat and temporal variation can both influence microbial community dynamics, although their relative importance in reservoir buffer zones with complex hydrology regimes and dramatically altered environments remains controversial. To elucidate this, we
Tengfei Yan, Zhengxin Wang, Zhen Wang, Yong Qin, Zheng Wang, Songwei Li   +5 more
doaj   +1 more source

Evaluation of the impact of climate change on the ecological resistance and ecological corridors based on set pair analysis theory

Ecological Indicators
Climate change significantly impacts ecological resistance and ecological corridors. However, the difficulty in evaluating this impact lies in two crucial issues: (i) the uncertainty arising from spatial heterogeneity, and (ii) the diversity of impacts ...
Yan Feng, Luo Ping, Wu Hongliang, Yao Jianglin   +3 more
doaj   +1 more source

Donor PBMC ranked by neutralization.

, 2012
PBMC from 19 donors were used as target cells for neutralization using 6 virus stocks and 7 neutralization reagents. The ranking and separation of donors into the upper two quartiles (“High neutralization") and the lower two quartiles (“Low ...
John C. Kappes (161603), Christina Ochsenbauer (161594), Jeffrey Currier (171750), Kara Lombardi (171744), Nelson Michael (171773), Bruce K. Brown (171729), Victoria R. Polonis (132293), Maggie Wesberry (171757), Gustavo Kijak (171738), David C. Montefiori (108747), Mary Marovich (171767), Viseth Ngauy (171761), Lindsay Wieczorek (171734)   +12 more
core   +1 more source

Charge‐Polarized Ni─S4 Single‐Atom Sites Drive Selective Photoreforming of Poly(lactic acid) to Lactate and Hydrogen

Advanced Functional Materials, EarlyView.
Atomically dispersed Ni–S4 sites on CdS nanorods induce interfacial charge polarization, directing photogenerated electrons to H2 evolution and holes to selective ester‐bond cleavage of poly(lactic acid). Without sacrificial reagents, this charge‐coupled system produces lactate while suppressing overoxidation, achieving an H2 evolution rate of 41.74 ...
Yu Yao, Panpan Zhang, Jinqiang Zhang, Xi‐lin Wu, Tara Pukala, Yifei Wang, Bernt Johannessen, Shaobin Wang, Xiaoguang Duan   +8 more
wiley   +1 more source

Labcode 3B- HIV neutralization testing with PBMC-based Neutralization Assay

This document describes the isolation of Peripheral Blood Mononuclear Cells (PBMCs) from buffycoat, the stimulation of PBMCs by PHA, and the determination of the neutralization sensitivity of HIV-1 strains using a PBMC neutralization ...
Scarlatti, Gabriella
core   +2 more sources