Results 191 to 200 of about 448,029 (330)

Neutralizing HSV [PDF]

Nature Immunology, 2019
openaire   +2 more sources

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Optimized ACE2-Fc fusion proteins with picomolar neutralization activity against highly evolved SARS-CoV-2 variants. [PDF]

Protein Sci
Abancó F, Tarrés-Freixas F, Lepore R, Molina-Molina E, Franco E, Boreika R, Pradenas E, Raïch-Regué D, Erkizia I, Clotet B, Valencia A, Vergara-Alert J, Segalés J, Carrillo J, Izquierdo-Useros N, Blanco J, Trinité B.   +16 more
europepmc   +1 more source

Advanced Structural Vaccinology and Mosaic Nanoparticles for the Rational Induction of Broadly Neutralizing Antibodies Against HIV: Circumventing the Extreme Hypervariability of the Viral Envelope

Barack Ndenga
openalex   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Post-attachment neutralization of HPV16 by antibodies derived from Gardasil-vaccinated women. [PDF]

NPJ Vaccines
Day PM, Thompson CD, Scherer EM, Carter JJ, Galloway DA, Lowy DR, Schiller JT.   +6 more
europepmc   +1 more source

Beyond blame: A systemic accident analysis through a neutralized human factors taxonomy [PDF]

Elena Stefana, Emanuele De Paola, Carlo Simone Snaiderbaur Bono, Francesco Bianchini, Tommaso Vagheggi, Riccardo Patriarca   +5 more
openalex   +1 more source

Decision letter: Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

, 2020
D Montefiore
openalex   +1 more source

Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific [PDF]

, 2015
Tina M. Cairns, Zhen-Yu Huang, John R. Gallagher, Yixin Lin, Huan Lou, J. Charles Whitbeck, Anna Wald, Gary H. Cohen, Roselyn J. Eisenberg   +8 more
openalex   +1 more source

A Hierarchically Structured, Stretchable, Anti‐Biofouling Encapsulation for Biodegradable Electronics

Advanced Healthcare Materials, EarlyView.
A soft, stretchable, anti‐biofouling encapsulant is developed by integrating organosilicon nanowire networks with microstructured biodegradable elastomers. The hierarchical surface exhibits superhydrophobicity and enhances water barrier properties by 420% over pristine polymers, while preserving mechanical integrity.
Won Bae Han, Sungkeun Han, Gwan‐Jin Ko, Ulziituya Batjargal, Wonjun Jang, Venkata Ramesh Naganaboina, Han‐Jun Kim, Suk‐Won Hwang   +7 more
wiley   +1 more source