Results 261 to 270 of about 454,570 (346)

Yeast Display Reveals Plentiful Mutations That Improve Fusion Peptide Vaccine-Elicited Antibodies Beyond 59% HIV-1 Neutralization Breadth. [PDF]

Vaccines (Basel)
França CT, Pletnev S, Madan B, Katsamba PS, McKee K, Morano NC, Zhang B, Bahna F, Bylund T, Lin BC, Louder MK, Mannepalli S, Nimrania R, O'Dell S, Doria-Rose NA, Kwong PD, Shapiro L, Sheng Z, Zhou T, DeKosky BJ.   +19 more
europepmc   +1 more source

3D Printing of Bacteriophage‐Loaded Hydrogels: Development of a Local and Long‐Lasting Delivery System

Advanced Healthcare Materials, EarlyView.
This research investigates the feasibility of 3D‐printing of a bacteriophage‐containing hydrogel made of alginate and methylcellulose. The printed hydrogels steadily release active bacteriophages for up to 35 days which is beneficial to treat implant‐associated infections.
Corina Vater, Gopala Krishna Mannala, Max von Witzleben, Richard Frank Richter, Nike Walter, Michael Gelinsky, Volker Alt, Anja Lode, Markus Rupp   +8 more
wiley   +1 more source

Immunogenicity of JN.1- and KP.2-Encoding mRNA COVID-19 Vaccines Against JN.1 Subvariants in Adult Participants. [PDF]

Open Forum Infect Dis
Figueroa AL, Girard B, Edwards DK, Nasir A, Johnson K, Hack S, Cao X, de Windt E, Urdaneta V, Priddy F, Das R, Montefiori DC, Chalkias S.   +12 more
europepmc   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Exceptionally broad HIV-1 neutralization via bispecific antibody-mediated prepositioning. [PDF]

Proc Natl Acad Sci U S A
Kim S, Travisano KA, Wilder B, Palomares M, Cao Z, Seaman MS, Kim PS.   +6 more
europepmc   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Structural Insights into the SARS-CoV-2 Spike Protein and Its Implications for Antibody Resistance. [PDF]

Biomolecules
Yamamoto Y, Noguchi K.
europepmc   +1 more source

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

Advanced Healthcare Materials, EarlyView.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf, Hendrik Bonnemeier, Ernest W. Lau, Jana Hummel, Reinhard Vonthein, Ojan Assadian   +5 more
wiley   +1 more source

Rotavirus-specific neutralization assay enables evaluation of mucosal immune responses. [PDF]

Front Immunol
Harzer M, Rückner A, Vahlenkamp TW.
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source