Results 171 to 180 of about 2,192,151 (309)

Structure-Based Adaptation of a SARS-CoV-2 Neutralizing Peptide to New Virus Variants. [PDF]

J Med Chem
Raasch N, Weißenborn L, Richel E, Schäfer S, Denysenko O, Bartelsen N, Sticht H, Überla K, Eichler J.   +8 more
europepmc   +1 more source

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

Advanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang, Xinyuan Ke, Andrew Heath, Richard J. Ball, Jiawei Xie, Jinchen Fan, Guisheng Li, Kevin Paine   +7 more
wiley   +1 more source

Multimerization and Conjugation to Antiviral and Cytotoxic Payloads Enhance the Activity of Virus-Neutralizing Nanobodies In Vitro. [PDF]

ACS Omega
Zhuchkov VA, Kruglova NA, Kamzeeva PN, Siniavin AE, Konovalova EV, Schulga AA, Gulyak EL, Sapozhnikova KA, Deyev SM, Yanvarev DV, Aralov AV, Chumakov SP.   +11 more
europepmc   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

The Intricate Nonadiabatic Dynamics of NO⁺ and NO₃^- Mutual Neutralization. [PDF]

J Am Chem Soc
Bogot A, Poline M, Ji MC, Dochain A, Martini P, Rosén S, Zettergren H, Schmidt HT, Thomas RD, Strasser D.   +9 more
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

A novel assay for quantifying Gn-LRP1-mediated neutralizing antibodies against severe fever with thrombocytopenia syndrome virus. [PDF]

Emerg Microbes Infect
Hu LF, Tu MY, Zhang DY, Sun MR, Liu SY, Li YY, Liu MY, Wang Y, Lim BL, Li JB, Tan CW, Wang LF.   +11 more
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Redox-neutral Mitsunobu Reaction

Journal of Synthetic Organic Chemistry, Japan, 2021
openaire   +2 more sources

Preparation and characterization of the affinity and neutralization abilities of human monoclonal antibodies against bunyavirus SFTSV glycoprotein C. [PDF]

Infect Med (Beijing)
Liu J, Ding Y, Zhu Y, Chi Y, Huang C, Chen Y, Shi F, Xu Y, Fu M, Cui L, Jiao Y.   +10 more
europepmc   +1 more source