Results 341 to 350 of about 1,883,437 (383)

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Biomimetic nanovaccines with self-adjuvant effects induced broad-spectrum neutralizing antibodies against SARS-CoV-2 infection in rodents. [PDF]

J Virol
Wang W, Du P, Zhao Y, Liang Y, Zhang C, Zhang H, Xia X, Liu B, Lei P, Yan F.   +9 more
europepmc   +1 more source

Host proteins associated with strong neutralizing SARS-CoV-2 antibody responses in a South African cohort

Khairallah, Afrah
openalex   +1 more source

SARS-CoV-2-Neutralizing Antibodies. [PDF]

Vaccines (Basel)
Liu Y, Nie J.
europepmc   +1 more source

Recurrent waning of anti-SARS-CoV-2 neutralizing antibodies despite multiple antigen encounters. [PDF]

J Transl Med
Pradenas E, Urrea V, Marfil S, Pidkova T, Aguilar-Gurrieri C, Abancó F, Mateu L, Chamorro A, Grau E, Trigueros M, Carrillo J, Massanella M, Trinité B, Clotet B, Blanco J.   +14 more
europepmc   +1 more source

Multiple infections with Omicron variants increase breadth and potency of Omicron-specific neutralizing antibodies. [PDF]

Cell Discov
You L, Zhang L, Ouyang S, Gao B, Li Y, Li J, Wu N, Wang H, Sun S, Li J, Yin Z, Xu Z, Chen Y, Zhu Y, Zhang S, Xu Z, Zhang T, Liu Z, Huang C, Li B, Qu J, Su B, Yeap LS.   +22 more
europepmc   +1 more source

IFN-α Neutralizing Antibodies Distinguish LADA From Early-onset Type 1 Diabetes.

J Clin Endocrinol Metab
Amendolara R, D'Onofrio L, Sessa RL, Di Giulio S, Mignogna C, Coraggio L, Schirano R, Zampetti S, Malandrucco I, Pozzilli P, Giannini G, Maddaloni E, Buzzetti R.   +12 more
europepmc   +1 more source

Versatile HIV Rev-dependent reporter cell system for stringent and sensitive quantification of viral reservoirs, neutralizing antibodies, and restriction factors

Spear M, Choi J, Hetrick B, Lee J, Lê-Bury G, Vo TT, Han Y, Liang H, Guo J, Yu D, Iyer S, Mwandumba HC, Russell DG, Wu Y, Gludish DW.   +14 more
europepmc   +1 more source

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Broadly Neutralizing Antiviral Antibodies

Annual Review of Immunology, 2013
A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive immune response. The widely held view has been that the great variability of viral glycoproteins would be an absolute obstacle to the development of antibody-based therapies or vaccines that could confer broad and long-lasting protection.
Corti D., Lanzavecchia A.
openaire   +2 more sources