Results 351 to 360 of about 1,883,437 (383)

Production of Neutralizing Antibody

2018
Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa, Shuang, Liu, Hitoshi, Hasegawa   +2 more
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Neutralization of HIV by Antibodies

2008
Antibodies can neutralize HIV-1 with potency and cross-reactivity that varies widely and is related but not correlated to their antigen-binding affinity. Therefore, in addition to measuring binding affinity, an evaluation of the antibody neutralizing activity in tissue cultures is important for development of antibody-based therapeutics, design of ...
Ilia, Prado, Timothy R, Fouts, Antony S, Dimitrov   +2 more
openaire   +2 more sources

Neutralizing antibody in rodent malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1975
Small numbers of rat erythrocytes infected with viable P. berghei, when inoculated into susceptible rats together with hyperimmune rat serum (HIS), are fully neutralized. Serum from convalescent rats delays the onset of patency but does not neutralize. The neutralizing efficiency of HIS rises in proportion to the number of successive reinoculations of ...
J, Golenser, D T, Spira, A, Zuckerman
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Antibody Neutralization in Hypoprothrombinaemic Plasma

Pathophysiology of Haemostasis and Thrombosis, 1972
The technique of antibody neutralization has been used to study the plasma of a large group of patients with hypoprothrombinaemia of diverse causes. The associated disorders included obstructive jaundice, acute infective hepatitis and chronic parenchymal liver disease. A number of patients were receiving warfarin and salicylate therapy. Irrespective of
J D, Parkin, F, Madaras, P A, Castaldi
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The secretion of virus-neutralizing antibodies

Archiv f�r die gesamte Virusforschung, 1967
Considerable evidence supports the concept that the immune defense against infectious agents that attack primarily the cells of the mucosal linings lies in secreted antibodies belonging to the IgA class of immunoglobulins. The problem that thus arises, in connection with the possible use of adjuvants in active immunization against these infectious ...
A, Giovanardi, A, Albano, L, Amante, S, De Donato, B, Pernis   +4 more
openaire   +2 more sources

Neutralizing antibodies and antigens in AIDS

Infection, 1991
Until recently, much of the effort put into development of an AIDS vaccine has focussed on the elicitation of a neutralizing antibody response. The viral target of neutralization, HIV envelope glycoprotein, has been produced in bulk through recombinant techniques, but has had little success as a vaccine.
S G, Norley, R, Kurth
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Neutralizing antibodies to interferon

Neurology, 2007
The impact of neutralizing antibodies (NAbs) to interferon-beta (IFN-beta) on clinical and imaging parameters in multiple sclerosis (MS) is reviewed. An effect on relapse rates and imaging parameters was noted in patients who tested positive for NAbs, but disability measures were unaffected or showed a trend toward improvement.
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Neutralizing antibody in nonallergic individuals

Journal of Allergy, 1952
Abstract Neutralizing antibody titrations were carried out in series of nonatopic human volunteers receiving one of the following ragweed preparations: (1) aqueous, (2) dialyzed aqueous, (3) alum precipitated, and (4) tannic acid precipitated extract. Also, extracts were made up to contain one of the following: (5) 10 per cent polyvinylpyrrolidone, (6)
S, MALKIEL, S M, FEINBERG
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Neutralization of Arenaviruses by Antibody

1987
Neutralization of infectivity is the end result of a number of alternative or synergistic reactions between a virus and antibody directed against certain antigenic determinants on its surface. These reactions prevent either the attachment of virus to a particular host cell by steric hindrance, the entry of virus into the cell, or the uncoating of the ...
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Neutralizing Antibodies Against Calcitonin

Hormone and Metabolic Research, 1993
The use of calcitonin (CT) is established as a treatment of Paget's disease of bone and postmenopausal osteoporosis (PMO). Salmon calcitonin (sCT), which differs in 14 of the 32 amino acids from human calcitonin, has found a wider distribution world wide, although antibody formation against sCT has been reported in more than 70% of the patients on ...
A, Grauer, H H, Reinel, R, Ziegler, F, Raue   +3 more
openaire   +2 more sources